黔南民族医专学报
黔南民族醫專學報
검남민족의전학보
JOURNAL OF QIANNAN MEDICAL COLLEGE FOR NATIONAL MINORITIES
2015年
1期
9-13
,共5页
谢伟杰%张永萍%徐剑%迮薇薇
謝偉傑%張永萍%徐劍%迮薇薇
사위걸%장영평%서검%책미미
原位凝胶%新型给药系统%评价方法%综述
原位凝膠%新型給藥繫統%評價方法%綜述
원위응효%신형급약계통%평개방법%종술
in situ gel%new drug delivery system%assessment method%review
原位凝胶新型给药系统,由于具有组织兼容、缓控释释放、靶向给药、多途径给药等独特优势,成为药剂学与生物技术领域的研究热点之一。参阅近几年相关研究报道,本文从制备与体外评价、剂型与给药途径、成型材料等几个方面进行概述,了解药学领域原位凝胶新型给药系统的研究动态。
原位凝膠新型給藥繫統,由于具有組織兼容、緩控釋釋放、靶嚮給藥、多途徑給藥等獨特優勢,成為藥劑學與生物技術領域的研究熱點之一。參閱近幾年相關研究報道,本文從製備與體外評價、劑型與給藥途徑、成型材料等幾箇方麵進行概述,瞭解藥學領域原位凝膠新型給藥繫統的研究動態。
원위응효신형급약계통,유우구유조직겸용、완공석석방、파향급약、다도경급약등독특우세,성위약제학여생물기술영역적연구열점지일。삼열근궤년상관연구보도,본문종제비여체외평개、제형여급약도경、성형재료등궤개방면진행개술,료해약학영역원위응효신형급약계통적연구동태。
Because of the unique advantages of tissue compatibility,slow release,targeting adminis-tration,multiple administration routes,in situ gel,as a new drug delivery system,has become one of the hotspots in pharmaceutical science and biotechnology fields. Referring to the relevant research reports in recent years,this review was given in several aspects, including preparation, in vitro evaluation, formulation, routes of administration,and molding materials,in order to understand the developments of this delivery sys-tem in the pharmaceutical field.