CAJ | 학술논문

目的探讨经股动脉行兔左心室及冠状动脉造影的方法和可行性,为研究心力衰竭和心肌梗死提供准确的心功能评估手段.方法新西兰大白兔20只,经股动脉置管后行左心室及冠状动脉造影,测量其左心室收缩期压力峰值(LVSP)、左心室舒张末压(LVEDP),计算左心室射血分数(LVEF).结果 12只兔成功行左心室及冠状动脉造影,兔平均LVEDP(5.08±2.01)mmHg(1mmHg=0.133 kPa),平均LVSP (101.04±21.12) mmHg,平均LVEF(68±7)％;5只兔穿刺置管失败,3只兔死亡.结论经兔股动脉行左心室及冠状动脉造影可行,能准确评估心功能,是一种可靠的方法,但条件要求较高.
목적 탐토경고동맥행토좌심실급관상동맥조영적방법화가행성,위연구심력쇠갈화심기경사제공준학적심공능평고수단.방법 신서란대백토20지,경고동맥치관후행좌심실급관상동맥조영,측량기좌심실수축기압력봉치(LVSP)、좌심실서장말압(LVEDP),계산좌심실사혈분수(LVEF).결과 12지토성공행좌심실급관상동맥조영,토평균LVEDP(5.08±2.01)mmHg(1mmHg=0.133 kPa),평균LVSP (101.04±21.12) mmHg,평균LVEF(68±7)％;5지토천자치관실패,3지토사망.결론 경토고동맥행좌심실급관상동맥조영가행,능준학평고심공능,시일충가고적방법,단조건요구교고.
Objective To investigate the feasibility of performing left ventricle and coronary artery angiography in rabbits through femoral artery as a method to provide accurate assessment of cardiac function in heart failure and myocardial infarction.Methods A total of 20 New Zealand rabbits were used and left ventricle and coronary artery angiography was performed through femoral artery.Peak left ventricular systolic pressure (LVSP),left ventricular end diastolic pressure (LVEDP) and left ventricular ejection fraction (LVEF) were recorded.Results Left ventricle and coronary artery angiography was successfully conducted in 12 rabbits,but failed in 5 rabbits during catheterization.The other 3 rabbits died during the procedure.The mean LVEDP was (5.08±2.01) mmHg (1 mmHg=0.133 kPa),the mean LVSP was (101.04±21.12) mmHg,and the mean LVEF (68±7) ％.Conclusions Left ventricle and coronary artery angiography through femoral artery in rabbits is feasible and can be used to accurately evaluate cardiac function.The method is reliable,but has strict requirements on equipment and training.