CAJ | 학술논문

目的探讨二维彩超联合实时剪切波弹性成像(SWE)检查在乳腺疾病诊断中的应用价值.方法选取2013年9月至2014年9月经病理证实的130例(158个)乳腺疾病患者,所有患者均行二维彩超和SWE检查.以受试者操作特性曲线(ROC)得出乳腺良恶性病变最大弹性模量值、平均弹性模量值的相应诊断临界值.依据病理检查结果,分别评价二维彩超和SWE诊断乳腺良恶性病变的敏感性、特异性和准确性,并比较2者的结果.结果 130例患者的158个乳腺病灶中,恶性病变90个,良性病变68个.二维彩超和SWE诊断乳腺癌的敏感性分别为89.7％和89.5％;特异性分别为85.6％和95.3％;准确性分别为87.3％和91.4％;二维彩超和SWE 2种方法联合检测诊断乳腺癌的敏感性、特异性、准确性分别为98.5％、93.3％、95.6％.结论二维彩超是诊断乳腺良恶性病变的常用检查方法,但是具有一定局限性.SWE检查可提高乳腺良恶性病变诊断的特异性,是传统二维彩超技术的有益补充.二维彩超与定量SWE技术联合应用,显著提高乳腺良恶性病变诊断的敏感性和准确性,为良恶性病变的鉴别诊断提供可靠依据,并且减少漏诊、误诊及不必要的活检,具有重要的临床应用价值.
목적 탐토이유채초연합실시전절파탄성성상(SWE)검사재유선질병진단중적응용개치.방법 선취2013년9월지2014년9월경병리증실적130례(158개)유선질병환자,소유환자균행이유채초화SWE검사.이수시자조작특성곡선(ROC)득출유선량악성병변최대탄성모량치、평균탄성모량치적상응진단림계치.의거병리검사결과,분별평개이유채초화SWE진단유선량악성병변적민감성、특이성화준학성,병비교2자적결과.결과 130례환자적158개유선병조중,악성병변90개,량성병변68개.이유채초화SWE진단유선암적민감성분별위89.7％화89.5％;특이성분별위85.6％화95.3％;준학성분별위87.3％화91.4％;이유채초화SWE 2충방법연합검측진단유선암적민감성、특이성、준학성분별위98.5％、93.3％、95.6％.결론 이유채초시진단유선량악성병변적상용검사방법,단시구유일정국한성.SWE검사가제고유선량악성병변진단적특이성,시전통이유채초기술적유익보충.이유채초여정량SWE기술연합응용,현저제고유선량악성병변진단적민감성화준학성,위량악성병변적감별진단제공가고의거,병차감소루진、오진급불필요적활검,구유중요적림상응용개치.
Objective To investigate two-dimensional color Doppler commissure real-time shear wave elastrography (SWE) examination and its application value in the diagnosis of breast diseases.Methods One hundred and thirty patients (158 breast lesions) confirmed with breast disease were chosen from September 2013 to September 2014,and all patients underwent two-dimensional color Doppler ultrasound and SWE examination.The receiver operating characteristic (ROC) curve was examined to obtain maximum elasticity modulus value,average elastic modulus value and the corresponding critical value for the diagnosis of benign and malignant breast lesions.According to the results of pathological examination,sensitivity,specificity and accuracy of two-dimensional ultrasound and SWE for the diagnosis of breast lesions were evaluated and compared.Results Of all 158 breast lesions in 130 patients,90 were malignant lesions and 68 were benign lesions.The sensitivities of two-dimensional ultrasound and SWE in diagnosis of breast cancer were 89.7％ and 89.5％,the specificities were 85.6％ and 95.3％ and the accuracy were 87.3％ and 91.4％,respectively.The sensitivity,specificity and accuracy in the diagnosis of breast cancer by combination of two-dimensional ultrasound and SWE were 98.5％,93.3％,95.6％,respectively.Conclusions Although two-dimensional color Doppler ultrasound is a commonly used method in the diagnosis of breast lesions,it has certain limitation.The specificity of diagnosis can be improved by SWE,which is a useful complement to traditional two-dimensional ultrasound technology.Combination of the two methods can significantly increase the sensitivity and accuracy of the diagnosis and provide a reliable basis for the differential diagnosis,reduce the rate of misdiagnosis,missed diagnosis and unnecessary biopsy,which has important clinical application value.