CAJ | 학술논문

目的应用生物电阻抗法(BIA)建立上海地区老年人肌少症骨骼肌质量诊断标准并开展上海地区老年人肌少症患病率的调查.方法对40例志愿者(年龄20～77岁)进行BIA和双能X线吸收仪(DEXA)检测,验证BIA测定瘦体组织的可靠性.对219例(年龄20～40岁)健康青年人(男∶女为100∶119)进行BIA检测,获得峰值肌量和老年人肌少症诊断切点.对657例≥60岁医院体检和社区老年人(男∶女为318∶339)进行BIA检测,了解上海地区老年人肌少症患病率.结果 BIA和DEXA检测瘦体组织差异无统计学意义(P=0.307).健康青年人四肢肌肉组织和身高平方的比值(ASM/身高2)男性和女性分别为(7.90±0.62)kg/m2和(6.12±0.44)kg/m2,老年人肌少症诊断标准男性和女性分别为≤6.66 kg/m2和≤5.24 kg/m2.将老年人分为3个年龄段,60～岁、70～岁和≥80岁3个年龄段男性肌少症的患病率分别为14.6％、25.0％和36.0％,女性分别为6.8％、12.6％和27.9％.老年男性整体患病率为23.6％,女性为11.8％.结论 BIA检测人体肌肉组织是可靠的,且随增龄肌少症患病率明显上升,男性高于女性.
목적 응용생물전조항법(BIA)건립상해지구노년인기소증골격기질량진단표준병개전상해지구노년인기소증환병솔적조사.방법 대40례지원자(년령20～77세)진행BIA화쌍능X선흡수의(DEXA)검측,험증BIA측정수체조직적가고성.대219례(년령20～40세)건강청년인(남∶녀위100∶119)진행BIA검측,획득봉치기량화노년인기소증진단절점.대657례≥60세의원체검화사구노년인(남∶녀위318∶339)진행BIA검측,료해상해지구노년인기소증환병솔.결과 BIA화DEXA검측수체조직차이무통계학의의(P=0.307).건강청년인사지기육조직화신고평방적비치(ASM/신고2)남성화녀성분별위(7.90±0.62)kg/m2화(6.12±0.44)kg/m2,노년인기소증진단표준남성화녀성분별위≤6.66 kg/m2화≤5.24 kg/m2.장노년인분위3개년령단,60～세、70～세화≥80세3개년령단남성기소증적환병솔분별위14.6％、25.0％화36.0％,녀성분별위6.8％、12.6％화27.9％.노년남성정체환병솔위23.6％,녀성위11.8％.결론 BIA검측인체기육조직시가고적,차수증령기소증환병솔명현상승,남성고우녀성.
Objective To establish diagnostic standard of sarcopenia using bioelectrical impedance analysis (BIA) and to obtain the prevalence of sarcopenia in the elderly in Shanghai.Methods 40 volunteers aged 20-77 years were enrolled and received BIA and dual-energy X-ray absorptiometry (DEXA) measurements in order to verify the reliability of BIA for measuring lean mass.219 healthy young volunteers aged 20 to 40 years with ratio of gender men:women 100:119 had BIA measurements to obtain peak muscle mass and sarcopenia diagnostic cut-off point of the elderly.657 elderly aged ≥ 60 years with ratio of gendermen:women 318:339 took BIA measurements to obtain the prevalence of sarcopenia in the elderly in Shanghai.Results No statistical difference between BIA-measured and DEXA-measured LM was observed (P =0.307).The appendicular skeletal muscle mass/height2 (ASM/h2) was (7.90 ± 0.62) kg/m2 in young men,and (6.12 ± 0.44)kg/m2 in young women,the cut off in elderly men and women were ≤6.66 kg/m2 and ≤ 5.24 kg/m2 respectively.Elderly people were divided into three age groups:aged60-69 years group,aged 70-69 years group,aged ≥ 80 years group,The prevalence of sarcopenia were 14.6％,25.0％ and 36.0％ in men and 6.8％,12.6％ and 27.9％ in women in aged 60-69 years,aged 70-69 years,aged ≥ 80years groups,respectively.The overall prevalence in elderly men and women were 23.6％ and 11.8％ respectively.Conclusions Measurement of LM by BIA is validated in Shanghai volunteers.The prevalence of sarcopenia in the elderly is increased with age,which is higher in elderly men than in elderly women.