中国医药
中國醫藥
중국의약
CHINA MEDICINE
2015年
6期
872-874
,共3页
王君%张军%于新平%李斌
王君%張軍%于新平%李斌
왕군%장군%우신평%리빈
妊娠%重度肺动脉高压%妊娠结局
妊娠%重度肺動脈高壓%妊娠結跼
임신%중도폐동맥고압%임신결국
Pregnancy%Severe pulmonary hypertension%Pregnancy outcome
目的 探讨妊娠合并重度肺动脉高压患者的妊娠结局.方法 回顾性分析首都医科大学附属北京安贞医院2007年1月至2014年11月收治的120例妊娠合并重度肺动脉高压患者的临床资料,分析其心脏病类型、心功能级别、终止妊娠方式和母婴结局.结果 120例患者中继发性肺动脉高压106例,其中继发于先天性心脏病者103例(85.8％),继发于风湿性心脏病者3例(2.5％);原发肺动脉高压者14例(11.7％).纽约心脏病协会心功能分析Ⅱ～Ⅳ级者119例(99.2％).孕早、中期医源性终止妊娠55例(45.8％),剖宫产61例(50.9％),自然分娩1例(0.8％),晚期难免流产2例(1.7％),母胎死亡1例(0.8％).孕产妇死亡9例(7.5％).围生儿62例,活产58例(93.5％),围生儿死亡4例(6.5％);新生儿窒息11例(17.7％),低体质量儿42例(67.7％).结论 妊娠合并重度肺动脉高压可危及母婴健康甚至生命,应早期终止妊娠.
目的 探討妊娠閤併重度肺動脈高壓患者的妊娠結跼.方法 迴顧性分析首都醫科大學附屬北京安貞醫院2007年1月至2014年11月收治的120例妊娠閤併重度肺動脈高壓患者的臨床資料,分析其心髒病類型、心功能級彆、終止妊娠方式和母嬰結跼.結果 120例患者中繼髮性肺動脈高壓106例,其中繼髮于先天性心髒病者103例(85.8％),繼髮于風濕性心髒病者3例(2.5％);原髮肺動脈高壓者14例(11.7％).紐約心髒病協會心功能分析Ⅱ～Ⅳ級者119例(99.2％).孕早、中期醫源性終止妊娠55例(45.8％),剖宮產61例(50.9％),自然分娩1例(0.8％),晚期難免流產2例(1.7％),母胎死亡1例(0.8％).孕產婦死亡9例(7.5％).圍生兒62例,活產58例(93.5％),圍生兒死亡4例(6.5％);新生兒窒息11例(17.7％),低體質量兒42例(67.7％).結論 妊娠閤併重度肺動脈高壓可危及母嬰健康甚至生命,應早期終止妊娠.
목적 탐토임신합병중도폐동맥고압환자적임신결국.방법 회고성분석수도의과대학부속북경안정의원2007년1월지2014년11월수치적120례임신합병중도폐동맥고압환자적림상자료,분석기심장병류형、심공능급별、종지임신방식화모영결국.결과 120례환자중계발성폐동맥고압106례,기중계발우선천성심장병자103례(85.8％),계발우풍습성심장병자3례(2.5％);원발폐동맥고압자14례(11.7％).뉴약심장병협회심공능분석Ⅱ～Ⅳ급자119례(99.2％).잉조、중기의원성종지임신55례(45.8％),부궁산61례(50.9％),자연분면1례(0.8％),만기난면유산2례(1.7％),모태사망1례(0.8％).잉산부사망9례(7.5％).위생인62례,활산58례(93.5％),위생인사망4례(6.5％);신생인질식11례(17.7％),저체질량인42례(67.7％).결론 임신합병중도폐동맥고압가위급모영건강심지생명,응조기종지임신.
Objective To evaluate the pregnancy outcomes of pregnant women with severe pulmonary hypertension.Methods Clinical data of 120 pregnant women with severe pulmonary hypertension from January 2007 to September 2014,including the types of heart disease,cardiac functional status,time and mode of pregnant termination and outcomes of the infants and mothers were retrospectively analyzed.Results There were 106 cases of secondary pulmonary hypertension [including 103 (85.8％) secondary to congenital heart disease and 3 (2.5％) secondary to rheumatic heart disease] and 14 cases (11.7％) of primary pulmonary hypertension.Totally 119 cases (99.2％) were New York Heart Association (NYHA) class Ⅱ-Ⅳ.In 120 patients,55 (45.8％) received iatrogenic abortion in the first and second trimester of pregnancy;61 (50.9％) received cesarean sections;1 underwent vaginal delivery (0.8％);inevitable abortion occurred in 2 (1.7％) in the third trimester of pregnancy;1 mother and her fetal (0.8％) died.Totally 9 mothers (7.5％) died.In 62 perinatal infants,there were 58 (93.5％) of live birth,4 (6.5％) of death,11 cases (17.7％) of neonate asphyxia and 42 cases (67.7％) of low weight.Conclusion Pregnancy in patients with severe pulmonary hypertension can increase the mobility and motality of the maternal and baby and it should be terminated as soon as possible.Cesarean section is a relatively safe way in the second and the third trimester of pregnancy.
