国际麻醉学与复苏杂志
國際痳醉學與複囌雜誌
국제마취학여복소잡지
INTERNATIONAL JOURNAL OF ANESTHESIOLOGY AND RESUSCITATION
2015年
5期
408-411
,共4页
朱蓓蓓%夏小萍%顾小萍%马正良
硃蓓蓓%夏小萍%顧小萍%馬正良
주배배%하소평%고소평%마정량
氟哌利多%术后镇痛%妇科腹腔镜手术
氟哌利多%術後鎮痛%婦科腹腔鏡手術
불고리다%술후진통%부과복강경수술
Droperidol%Postoperative analgesia%Laparoscopy surgery
目的 观察预先静脉注射氟哌利多对妇科腹腔镜手术术后的镇痛效果及舒适度的影响.方法 美国麻醉医师协会(ASA)分级Ⅰ～Ⅱ级择期行妇科腹腔镜手术的患者46例,按随机数字表法分成两组(每组23例):氟哌利多组(D组,手术切皮前静脉注射氟派利多2.5 mg)和对照组(C组,手术切皮前静脉注射生理盐水2 ml).记录两组患者一般情况(年龄、身高、体重)、手术时间,记录入手术室、诱导后、入麻醉后监测治疗室(post-anesthesia care unit,PACU)时、苏醒时、拔管后及离开PACU时患者的平均动脉压(mean arterial pressure,MAP)、心率(heart rate,HR),术后送入PACU观察停止麻醉后患者睁眼时间、拔管时间;记录拔管后即时及拔管后30 min时Ramsay镇静评分及改良-Aldrete评分,拔管后30 min、1h及术后6、24 h数字评价量表(numerical rating scale,NRS)评分及恶心呕吐、寒战等副作用的发生率.结果 两组患者术前基础情况差异无统计学意义(P＞0.05).NRS评分:拔管后30 min、1h、术后6、24 h时,D组[(1.4±1.3)、(1.7±1.5)、(1.5±1.5)、(0.9±0.8)分]与C组[(3.5±1.6)、(3.7±1.5)、(3.4±1.8)、(2.4±1.4)分]比较,差异均有统计学意义(P＜0.05).两组各时间点MAP、HR等比较,差异无统计学意义(P＞0.05).两组Ramsay镇静评分及改良-Aldrete评分比较,差异无统计学意义(P＞0.05).C组恶心呕吐发生率高于D组,差异有统计学意义(P＜0.05);两组患者均未出现苏醒后呼吸抑制、精神障碍、锥体外系反应等副作用.结论 预先静脉给予氟哌利多有良好的术后镇痛效果,同时可降低术后恶心呕吐的发生率,提高患者舒适度.
目的 觀察預先靜脈註射氟哌利多對婦科腹腔鏡手術術後的鎮痛效果及舒適度的影響.方法 美國痳醉醫師協會(ASA)分級Ⅰ～Ⅱ級擇期行婦科腹腔鏡手術的患者46例,按隨機數字錶法分成兩組(每組23例):氟哌利多組(D組,手術切皮前靜脈註射氟派利多2.5 mg)和對照組(C組,手術切皮前靜脈註射生理鹽水2 ml).記錄兩組患者一般情況(年齡、身高、體重)、手術時間,記錄入手術室、誘導後、入痳醉後鑑測治療室(post-anesthesia care unit,PACU)時、囌醒時、拔管後及離開PACU時患者的平均動脈壓(mean arterial pressure,MAP)、心率(heart rate,HR),術後送入PACU觀察停止痳醉後患者睜眼時間、拔管時間;記錄拔管後即時及拔管後30 min時Ramsay鎮靜評分及改良-Aldrete評分,拔管後30 min、1h及術後6、24 h數字評價量錶(numerical rating scale,NRS)評分及噁心嘔吐、寒戰等副作用的髮生率.結果 兩組患者術前基礎情況差異無統計學意義(P＞0.05).NRS評分:拔管後30 min、1h、術後6、24 h時,D組[(1.4±1.3)、(1.7±1.5)、(1.5±1.5)、(0.9±0.8)分]與C組[(3.5±1.6)、(3.7±1.5)、(3.4±1.8)、(2.4±1.4)分]比較,差異均有統計學意義(P＜0.05).兩組各時間點MAP、HR等比較,差異無統計學意義(P＞0.05).兩組Ramsay鎮靜評分及改良-Aldrete評分比較,差異無統計學意義(P＞0.05).C組噁心嘔吐髮生率高于D組,差異有統計學意義(P＜0.05);兩組患者均未齣現囌醒後呼吸抑製、精神障礙、錐體外繫反應等副作用.結論 預先靜脈給予氟哌利多有良好的術後鎮痛效果,同時可降低術後噁心嘔吐的髮生率,提高患者舒適度.
목적 관찰예선정맥주사불고리다대부과복강경수술술후적진통효과급서괄도적영향.방법 미국마취의사협회(ASA)분급Ⅰ～Ⅱ급택기행부과복강경수술적환자46례,안수궤수자표법분성량조(매조23례):불고리다조(D조,수술절피전정맥주사불파리다2.5 mg)화대조조(C조,수술절피전정맥주사생리염수2 ml).기록량조환자일반정황(년령、신고、체중)、수술시간,기록입수술실、유도후、입마취후감측치료실(post-anesthesia care unit,PACU)시、소성시、발관후급리개PACU시환자적평균동맥압(mean arterial pressure,MAP)、심솔(heart rate,HR),술후송입PACU관찰정지마취후환자정안시간、발관시간;기록발관후즉시급발관후30 min시Ramsay진정평분급개량-Aldrete평분,발관후30 min、1h급술후6、24 h수자평개량표(numerical rating scale,NRS)평분급악심구토、한전등부작용적발생솔.결과 량조환자술전기출정황차이무통계학의의(P＞0.05).NRS평분:발관후30 min、1h、술후6、24 h시,D조[(1.4±1.3)、(1.7±1.5)、(1.5±1.5)、(0.9±0.8)분]여C조[(3.5±1.6)、(3.7±1.5)、(3.4±1.8)、(2.4±1.4)분]비교,차이균유통계학의의(P＜0.05).량조각시간점MAP、HR등비교,차이무통계학의의(P＞0.05).량조Ramsay진정평분급개량-Aldrete평분비교,차이무통계학의의(P＞0.05).C조악심구토발생솔고우D조,차이유통계학의의(P＜0.05);량조환자균미출현소성후호흡억제、정신장애、추체외계반응등부작용.결론 예선정맥급여불고리다유량호적술후진통효과,동시가강저술후악심구토적발생솔,제고환자서괄도.
Objective To evaluate the effect of droperidol pretreatment on postoperative pain and comfort in patients undergoing gynecologic laparoscopic surgery.Methods Forty-six female patients undergoing gynecologic laparoscopic surgery were divided into two groups randomly(n=23):the patients were treated with droperidol intravenously(group D),while patients were given with placebo as control (group C).General characteristics of patients in two groups were recorded,including age,height,weight,operation time,postoperative recovery time,and endotracheal extubation time.Ramsay score and M-Aldrete score immediately and 30 min after extubation were recorded.The postoperative pain scores of all patients were recorded at the time point of 30 min,1,6 h and 24 h after endotracheal extubation by numerical rating scale (NRS).Postoperative incidence of nausea and vomiting and other side effects were recorded.Results General characteristics of patients in both groups were similiar(P＞0.05).Compared with group C [(3.5±1.6),(3.7±1.5),(3.4±1.8),(2.4±1.4)],the NRS in group D[(1.4±1.3),(1.7±1.5),(1.5±1.5),(0.9±0.8)] was significantly lower at 30 min and 1 h after endotracheal extubation and 6,24 h after operation respectively (P＜0.05).Difference between the two groups was not statistically significant at each time point in mean arterial pressure and heart rate (P＞0.05).There was no significant difference of Ramsay score and M-Aldrete score in both groups.The incidence of postoperative nausea and vomiting was significantly higher in group C(P＜0.05).There were no respiratory depression,mental disorders,extrapyramidal reactions and other side effects in the two groups.Conclusions Droperidol pretreatment provides a significant analgesic benefit and makes patients undergoing gynecologic laparoscopic surgery comfortable.
