中国医药
中國醫藥
중국의약
CHINA MEDICINE
2015年
6期
788-790
,共3页
蒋彬%余平安%陈中琦%王劲松
蔣彬%餘平安%陳中琦%王勁鬆
장빈%여평안%진중기%왕경송
冠状动脉疾病%血脂%胆红素%总胆汁酸
冠狀動脈疾病%血脂%膽紅素%總膽汁痠
관상동맥질병%혈지%담홍소%총담즙산
Coronary heart disease%Blood lipids%Bilirubin%Total bile acid
目的 探讨血脂、血清胆红素、总胆汁酸检测对冠状动脉粥样硬化性心脏病(冠心病)患者的临床意义.方法 纳入浙江省建德市第一人民医院2012年1月至2014年1月确诊的170例冠心病患者作为观察组,以同期150例健康体检者作为对照组.抽取清晨空腹静脉血检测血脂、血清胆红素、总胆汁酸水平,并做对比分析.结果 观察组总胆固醇、三酰甘油、低密度脂蛋白胆固醇(LDL-C)、三酰甘油/高密度脂蛋白胆固醇(HDL-C)、LDL-C/HDL-C、总胆汁酸明显高于对照组[(5.92±1.03) mmol/L比(4.57±0.68) mmol/L、(2.81±0.39) mmol/L比(1.36±0.24) mmol/L、(4.16±1.38) mmol/L比(2.54±0.76) mmol/L、(2.74±0.36)比(1.21±0.48)、(4.08±0.73)比(2.92 ±0.51)、(17.0±7.5) μmol/L比(6.4±4.9) μmol/L] (P ＜0.01),HDL-C、总胆红素、直接胆红素、间接胆红素浓度均低于对照组[(1.17±0.23) mmol/L比(1.79±0.84) mmol/L、(10.0±3.9) μmol/L比(14.4±3.6) μmol/L、(3.3 ± 1.5) μmol/L比(5.0±2.4) μmol/L、(9.7±2.6) μmol/L比(11.8±2.7)μmol/L],差异均有统计学意义(均P＜0.01).结论 血脂、血清胆红素与总胆汁酸在冠心病中出现异常,对临床诊断与治疗有重要指导意义.
目的 探討血脂、血清膽紅素、總膽汁痠檢測對冠狀動脈粥樣硬化性心髒病(冠心病)患者的臨床意義.方法 納入浙江省建德市第一人民醫院2012年1月至2014年1月確診的170例冠心病患者作為觀察組,以同期150例健康體檢者作為對照組.抽取清晨空腹靜脈血檢測血脂、血清膽紅素、總膽汁痠水平,併做對比分析.結果 觀察組總膽固醇、三酰甘油、低密度脂蛋白膽固醇(LDL-C)、三酰甘油/高密度脂蛋白膽固醇(HDL-C)、LDL-C/HDL-C、總膽汁痠明顯高于對照組[(5.92±1.03) mmol/L比(4.57±0.68) mmol/L、(2.81±0.39) mmol/L比(1.36±0.24) mmol/L、(4.16±1.38) mmol/L比(2.54±0.76) mmol/L、(2.74±0.36)比(1.21±0.48)、(4.08±0.73)比(2.92 ±0.51)、(17.0±7.5) μmol/L比(6.4±4.9) μmol/L] (P ＜0.01),HDL-C、總膽紅素、直接膽紅素、間接膽紅素濃度均低于對照組[(1.17±0.23) mmol/L比(1.79±0.84) mmol/L、(10.0±3.9) μmol/L比(14.4±3.6) μmol/L、(3.3 ± 1.5) μmol/L比(5.0±2.4) μmol/L、(9.7±2.6) μmol/L比(11.8±2.7)μmol/L],差異均有統計學意義(均P＜0.01).結論 血脂、血清膽紅素與總膽汁痠在冠心病中齣現異常,對臨床診斷與治療有重要指導意義.
목적 탐토혈지、혈청담홍소、총담즙산검측대관상동맥죽양경화성심장병(관심병)환자적림상의의.방법 납입절강성건덕시제일인민의원2012년1월지2014년1월학진적170례관심병환자작위관찰조,이동기150례건강체검자작위대조조.추취청신공복정맥혈검측혈지、혈청담홍소、총담즙산수평,병주대비분석.결과 관찰조총담고순、삼선감유、저밀도지단백담고순(LDL-C)、삼선감유/고밀도지단백담고순(HDL-C)、LDL-C/HDL-C、총담즙산명현고우대조조[(5.92±1.03) mmol/L비(4.57±0.68) mmol/L、(2.81±0.39) mmol/L비(1.36±0.24) mmol/L、(4.16±1.38) mmol/L비(2.54±0.76) mmol/L、(2.74±0.36)비(1.21±0.48)、(4.08±0.73)비(2.92 ±0.51)、(17.0±7.5) μmol/L비(6.4±4.9) μmol/L] (P ＜0.01),HDL-C、총담홍소、직접담홍소、간접담홍소농도균저우대조조[(1.17±0.23) mmol/L비(1.79±0.84) mmol/L、(10.0±3.9) μmol/L비(14.4±3.6) μmol/L、(3.3 ± 1.5) μmol/L비(5.0±2.4) μmol/L、(9.7±2.6) μmol/L비(11.8±2.7)μmol/L],차이균유통계학의의(균P＜0.01).결론 혈지、혈청담홍소여총담즙산재관심병중출현이상,대림상진단여치료유중요지도의의.
Objective To explore the clinical significance of the levels of blood lipids,serum bilirubin and total bile acid in coronary heart disease.Methods Totally 170 patients with coronary heart disease (CHD) from January 2012 to January 2014 were selected as observation group and 150 healthy people were set as control group.The morning fasting venous blood was obtained to detect the levels of blood lipids,serum bilirubin and total bile acid by automatic biochemical analyzer and the results were compared between the two groups.Results The level of total cholesterol,triacylglycerol,low density lipoprotein cholesterol (LDL-C),triacylglycerol/high density lipoprotein cholesterol (HDL-C),LDL-C/HDL-C and total bile acid in observation group was significantly higher than those in control group[(5.92 ± 1.03) mmol/L vs (4.57 ±0.68) mmol/L,(2.81 ±0.39) mmol/L vs (1.36±0.24) mmol/L,(4.16±1.38) mmol/L vs (2.54 ±0.76) mmol/L,(2.74 ±0.36) vs (1.21 ± 0.48),(4.08 ±0.73) vs (2.92 ±0.51),(17.0 ±7.5) μmol/L vs (6.4 ±4.9) μmol/L,P ＜0.01],and the levels of HDL-C,total bilirubin,direct bilirubin,indirect bilirubin in observation group were significantly lower than those in control group [(1.17±0.23) mmol/L vs (1.79±0.84) mmol/L,(10.0 ±3.9) μmol/L vs (14.4±3.6) mol/L,(3.3 ±1.5) μmol/L vs (5.0±2.4)μmol/L,(9.7±2.6) μmol/L vs (11.8±2.7) μmol/L] (P ＜ 0.01).Conclusion The levels of blood lipids,serum bilirubin and total bile acid were abnormal in patients with CHD.
