中国医药
中國醫藥
중국의약
CHINA MEDICINE
2015年
6期
801-804
,共4页
李文秀%耿斌%苏俊武%吴江%杨爽
李文秀%耿斌%囌俊武%吳江%楊爽
리문수%경빈%소준무%오강%양상
法洛四联症%动脉导管缺如%血流逆灌
法洛四聯癥%動脈導管缺如%血流逆灌
법락사련증%동맥도관결여%혈류역관
Tetralogy of Fallot%Absent ductus arteriosus%Inverse color flow
目的 探讨胎儿法洛四联症(TOF)合并动脉导管缺如或动脉导管血流逆灌的肺动脉主干及其分支发育情况.方法 回顾性分析2010年1月至2014年6月46例胎儿法洛四联症的超声心动图检查结果,根据是否存在动脉导管分为单纯TOF组、TOF合并动脉导管缺如组、TOF合并动脉导管血流逆灌组;对比分析各组肺动脉主干及其分支的发育情况.结果 46例胎儿中,单纯TOF组26例,TOF合并动脉导管缺如组12例,TOF合并动脉导管血流逆灌组8例;TOF合并动脉导管血流逆灌组肺动脉主干发育最差,其主动脉与肺动脉主干内径的比值与单纯TOF组、TOF合并动脉导管缺如组比较差异均有统计学意义[(2.07±0.78)比(1.54±0.47)、(1.40±0.15),均P＜0.05],各组间主动脉与肺动脉分支内径比值及肺动脉分支内径≤2 mm比例差异均无统计学意义(均P＞0.05).结论 TOF出现动脉导管血流逆灌时肺动脉主干发育较单纯TOF和TOF合并动脉导管缺如者更差,在胎儿期诊断TOF时,要重视肺动脉的发育情况,并要注意动脉导管的检查,特别是动脉导管血流逆灌.
目的 探討胎兒法洛四聯癥(TOF)閤併動脈導管缺如或動脈導管血流逆灌的肺動脈主榦及其分支髮育情況.方法 迴顧性分析2010年1月至2014年6月46例胎兒法洛四聯癥的超聲心動圖檢查結果,根據是否存在動脈導管分為單純TOF組、TOF閤併動脈導管缺如組、TOF閤併動脈導管血流逆灌組;對比分析各組肺動脈主榦及其分支的髮育情況.結果 46例胎兒中,單純TOF組26例,TOF閤併動脈導管缺如組12例,TOF閤併動脈導管血流逆灌組8例;TOF閤併動脈導管血流逆灌組肺動脈主榦髮育最差,其主動脈與肺動脈主榦內徑的比值與單純TOF組、TOF閤併動脈導管缺如組比較差異均有統計學意義[(2.07±0.78)比(1.54±0.47)、(1.40±0.15),均P＜0.05],各組間主動脈與肺動脈分支內徑比值及肺動脈分支內徑≤2 mm比例差異均無統計學意義(均P＞0.05).結論 TOF齣現動脈導管血流逆灌時肺動脈主榦髮育較單純TOF和TOF閤併動脈導管缺如者更差,在胎兒期診斷TOF時,要重視肺動脈的髮育情況,併要註意動脈導管的檢查,特彆是動脈導管血流逆灌.
목적 탐토태인법락사련증(TOF)합병동맥도관결여혹동맥도관혈류역관적폐동맥주간급기분지발육정황.방법 회고성분석2010년1월지2014년6월46례태인법락사련증적초성심동도검사결과,근거시부존재동맥도관분위단순TOF조、TOF합병동맥도관결여조、TOF합병동맥도관혈류역관조;대비분석각조폐동맥주간급기분지적발육정황.결과 46례태인중,단순TOF조26례,TOF합병동맥도관결여조12례,TOF합병동맥도관혈류역관조8례;TOF합병동맥도관혈류역관조폐동맥주간발육최차,기주동맥여폐동맥주간내경적비치여단순TOF조、TOF합병동맥도관결여조비교차이균유통계학의의[(2.07±0.78)비(1.54±0.47)、(1.40±0.15),균P＜0.05],각조간주동맥여폐동맥분지내경비치급폐동맥분지내경≤2 mm비례차이균무통계학의의(균P＞0.05).결론 TOF출현동맥도관혈류역관시폐동맥주간발육교단순TOF화TOF합병동맥도관결여자경차,재태인기진단TOF시,요중시폐동맥적발육정황,병요주의동맥도관적검사,특별시동맥도관혈류역관.
Objective To explore the developmental state of pulmonary artery trunk and the branch vessels in fetus with tetralogy of Fallot (TOF) complicated with absent ductus arteriosus or inverse flow in ductus arteriosus by prenatal echocardiography.Methods Echocardiography results of 46 fetuses with TOF from January 2010 to June 2014 were retrospectively analyzed.The cases were divided into isolated TOF group (group Ⅰ),TOF complicated with absent ductus arteriosus group (group Ⅱ) and TOF complicated with inverse flow in ductus arteriosus group (group Ⅲ).The analysis of pulmonary artery trunk and branch vessels were evaluated and compared among three groups.Results In 46 cases,there were 26 cases in group Ⅰ,12 cases in group Ⅱ and 8 in group Ⅲ.The main pulmonary artery trunk was worst in group Ⅲ compared with group Ⅱ and Ⅲ;the diameter ratio of aorta and pulmonary artery trunk in Ⅲ group was the highest [(2.07 ±0.78) vs (1.54 ± 0.47),(1.40 ± 0.15),all P ＜ 0.05].There were no statistical differences in diameter ratio of aorta and pulmonary artery branch vessels among three groups,so was the proportion of fetal with pulmonary artery branch diameter ≤2 mm (all P ＞ 0.05).Conclusion In TOF fetuses complicated with inverse flow in ductus arteriosus,the development of pulmonary artery trunk is the worse compared with isolated TOF and TOF complicated with absent ductus arteriosus.
