CAJ | 학술논문

目的：探讨超难治性癫痫持续状态的诊断、治疗和预后。方法回顾分析了2009年10月收治的1例癫痫持续状态的患者，先后静脉给予地西泮、氯硝西泮和咪达唑仑等常规药物治疗，其癫痫发作才逐渐得到控制。检索复习癫痫持续状态的相关文献。结果目前国内外未见大宗样本报道。诊断尚存在争议，但治疗原则较为一致，采用渐进性贯序疗法。结论癫痫持续状态多由于严重的脑损伤导致，但某些患者没有明确病因也可能出现难治性癫痫持续状态。治疗多采用阶梯式治疗方法，预后较差。
목적：탐토초난치성전간지속상태적진단、치료화예후。방법회고분석료2009년10월수치적1례전간지속상태적환자，선후정맥급여지서반、록초서반화미체서륜등상규약물치료，기전간발작재축점득도공제。검색복습전간지속상태적상관문헌。결과목전국내외미견대종양본보도。진단상존재쟁의，단치료원칙교위일치，채용점진성관서요법。결론전간지속상태다유우엄중적뇌손상도치，단모사환자몰유명학병인야가능출현난치성전간지속상태。치료다채용계제식치료방법，예후교차。
Objective To explore the definition , diagnosis and therapy of super-refractory status epilepticus ( SRSE ) .Methods The clinical data of one patients with super-refractory status epilepticus ( SE ) treated in October 2009 and the seizure was gradually controlled after the intravenous routine drug therapy ,were analyzed retrospectively .The literature on super-refractory SE was also reviewed .Results Data about SRSE was scarce .The diagnosis and definition of SRSE was controversial , but experts have consensus on the treatment .A protocol has been recommended on numerous occasions .Conclusions Usually, this condition occurs because of serious brain damage , nevertheless , some patients develop super-refractory SE without identifiable etiology .A protocol for managing SRSE is suggested , but the outcome is not very good .