浙江化工
浙江化工
절강화공
ZHEJIANG CHEMICAL INDUSTRY
2015年
4期
23-25
,共3页
徐玉崇%秦宝福%房凤香%韩德全%张明明
徐玉崇%秦寶福%房鳳香%韓德全%張明明
서옥숭%진보복%방봉향%한덕전%장명명
克林霉素磷酸酯%水解液%碱性试剂%无水碳酸钠
剋林黴素燐痠酯%水解液%堿性試劑%無水碳痠鈉
극림매소린산지%수해액%감성시제%무수탄산납
clindamycin phosphate%hydrolysate%neutralizing reagent%sodium carbonate
研究了克林霉素磷酸酯合成后处理工艺优化、在后处理操作步骤中上柱前水解液调碱的问题；选择不同的碱性试剂调节水解液的pH，得到最佳调节剂为饱和的无水碳酸钠，经实验验证，工艺稳定可行。
研究瞭剋林黴素燐痠酯閤成後處理工藝優化、在後處理操作步驟中上柱前水解液調堿的問題；選擇不同的堿性試劑調節水解液的pH，得到最佳調節劑為飽和的無水碳痠鈉，經實驗驗證，工藝穩定可行。
연구료극림매소린산지합성후처리공예우화、재후처리조작보취중상주전수해액조감적문제；선택불동적감성시제조절수해액적pH，득도최가조절제위포화적무수탄산납，경실험험증，공예은정가행。
This paper discussed choosing different alkaline reagents regulation hydrolyzate pH. We con-firmed that saturated anhydrous sodium carbonate was the best regulator, the experimental verification pro-cess is stable.The process which were verified through masses of experiments was stable.
