CAJ | 학술논문

目的：分析川西獐牙菜（Swertia mussotii Franch）的活性化学成分对亚硝基（NO 2－）的清除作用，为寻找川西獐牙菜的防癌活性成分提供科学依据。方法：使用紫外分光光度法测定亚硝基的含量，根据活性追踪的结果筛选出对 NO 2－有较好的清除作用的口山酮类化合物。结果：川西獐牙菜乙醇提取物的正丁醇萃取部位对 NO 2－的清除率最高，并筛分出清除能力最好的化合物是7－羟基－3，4，8－三甲氧基－1－O －β－D －吡喃葡萄糖－口山酮苷。结论：川西獐牙菜清除 NO 2－的活性物质是一些极性较大的化合物，为进一步研究川西獐牙菜的防癌作用及相关产品的开发奠定了实验基础。
목적：분석천서장아채（Swertia mussotii Franch）적활성화학성분대아초기（NO 2－）적청제작용，위심조천서장아채적방암활성성분제공과학의거。방법：사용자외분광광도법측정아초기적함량，근거활성추종적결과사선출대 NO 2－유교호적청제작용적구산동류화합물。결과：천서장아채을순제취물적정정순췌취부위대 NO 2－적청제솔최고，병사분출청제능력최호적화합물시7－간기－3，4，8－삼갑양기－1－O －β－D －필남포도당－구산동감。결론：천서장아채청제 NO 2－적활성물질시일사겁성교대적화합물，위진일보연구천서장아채적방암작용급상관산품적개발전정료실험기출。
Objective To analyze the scavenging effect of active chemica constituents from Swertia mussotii on NO 2 -,To provide a scientific basis for searching the anti -cancer active components from Swertia mussotii.Method the UV spectrophotometry was used to determine the NO 2 - content,screening out xanthone compounds with the effect to scavenge NO 2 - according to the active tracking results.Results The n -butanol fraction of the ethanol extracted of Swertia mussotii showed a highestscavenging rate,and 7 -hydroxy-3,4,8 -trimethoxy -1 -O -β-D -glucopyranosyl -xanthone is the best compounds from the Screening experiment.Conclu-sion The active substances with the effect to scavenge NO 2 - is high polar compounds in Swertia mussotii.This result should lay a the-oretical foundation for the further research on the cancer prevention of Swertia mussotii and development of the relevant products.