CAJ | 학술논문

为了消除肿瘤对人类健康的危害,治疗性肿瘤疫苗的研发日益受到人们的重视.相对于传统治疗手段,肿瘤免疫治疗具有靶向性高、对机体伤害小的优点.本文首先对肿瘤的免疫逃脱机制进行了探讨,并对治疗性肿瘤疫苗的设计原则,以及各种治疗性肿瘤疫苗的最新研究进展以及应用进行了回顾,最后对肿瘤疫苗的发展进行了展望.
위료소제종류대인류건강적위해,치료성종류역묘적연발일익수도인문적중시.상대우전통치료수단,종류면역치료구유파향성고、대궤체상해소적우점.본문수선대종류적면역도탈궤제진행료탐토,병대치료성종류역묘적설계원칙,이급각충치료성종류역묘적최신연구진전이급응용진행료회고,최후대종류역묘적발전진행료전망.
To eliminate cancer hazards to human health,the development of the therapeutic cancer vaccine has been given more and more attention.By contrast of tradition therapy,cancer immunotherapy take the advantage of being able to achieve target therapy and take modest harm to organism.Here,we first idiscussed the mechanisms of cancer immune escape,and reviewed the design principles of therapeutic cancer vaccine,as well as the latest research progress of therapeutic cancer vaccine and its application.