中华肝胆外科杂志
中華肝膽外科雜誌
중화간담외과잡지
CHINESE JOURNAL OF HEPATOBILIARY SURGERY
2015年
5期
297-300
,共4页
陆文%范晴敏%吴盼盼%徐中琪%许赟%钱国军
陸文%範晴敏%吳盼盼%徐中琪%許赟%錢國軍
륙문%범청민%오반반%서중기%허빈%전국군
肝癌%微波消融%乙肝病毒再激活
肝癌%微波消融%乙肝病毒再激活
간암%미파소융%을간병독재격활
Hepatocellular carcinoma%Microwave ablation%Hepatitis B virus reactivation
目的 探讨乙型肝炎相关性肝癌患者行微波消融(MWA)术后乙型肝炎病毒(HBV)再激活的风险及预后.方法 前瞻性研究72例符合入组标准的患者.其中30例为对照组,42例为预防性抗病毒组.探讨两组患者术后HBV再激活率及肝功能恢复情况等指标.结果 在随访期间8.3% (6/72)患者出现乙肝病毒再激活.高HBV DNA载量和未行预防性抗病毒治疗是HBV再激活的独立危险因素.HBV再激活是肝癌复发的危险因素(P<0.05).结论 HBV再激活能导致肝癌复发,预防性抗病毒治疗能有效控制HBV再激活.
目的 探討乙型肝炎相關性肝癌患者行微波消融(MWA)術後乙型肝炎病毒(HBV)再激活的風險及預後.方法 前瞻性研究72例符閤入組標準的患者.其中30例為對照組,42例為預防性抗病毒組.探討兩組患者術後HBV再激活率及肝功能恢複情況等指標.結果 在隨訪期間8.3% (6/72)患者齣現乙肝病毒再激活.高HBV DNA載量和未行預防性抗病毒治療是HBV再激活的獨立危險因素.HBV再激活是肝癌複髮的危險因素(P<0.05).結論 HBV再激活能導緻肝癌複髮,預防性抗病毒治療能有效控製HBV再激活.
목적 탐토을형간염상관성간암환자행미파소융(MWA)술후을형간염병독(HBV)재격활적풍험급예후.방법 전첨성연구72례부합입조표준적환자.기중30례위대조조,42례위예방성항병독조.탐토량조환자술후HBV재격활솔급간공능회복정황등지표.결과 재수방기간8.3% (6/72)환자출현을간병독재격활.고HBV DNA재량화미행예방성항병독치료시HBV재격활적독립위험인소.HBV재격활시간암복발적위험인소(P<0.05).결론 HBV재격활능도치간암복발,예방성항병독치료능유효공제HBV재격활.
Objective To investigate the risk factors of hepatitis B virus (HBV) reactivation after microwave ablation (MWA) and its prevention.Methods 72 patients who met the inclusion criteria were enrolled into the study.30 patients were in the control group and 42 patients in the prophylactic antivirus group.Results 8.3% (6/72) patients developed HBV reactivation.A high HBV DNA load and no prophylactic antivirus therapy were independent risk factors of viral reactivation.Conclusion Prophylactic antivirus therapy can prevent HBV reactivation.