CAJ | 학술논문

目的探讨非创伤性脾破裂的病因、发病机制、诊治方法.方法回顾性分析首都医科大学大兴医院非创伤性脾破裂5例患者的临床资料,并结合相关文献进行分析讨论.结果非创伤性脾破裂患者男性多见,平均年龄大.该病病因较多,以血液病、病毒感染、局部炎症和肿瘤多见.发病机制与脾脏增大、脆性增加、凝血障碍、脾位置异常、膈肌强烈收缩等有关.其确诊较创伤性脾破裂困难.治疗以手术为主,部分患者也可行非手术治疗.其预后与病因、年龄有关.结论非创伤性脾破裂病因较多,病理性脾破裂占绝大多数,临床诊断困难,治疗以脾切除术为主.
목적 탐토비창상성비파렬적병인、발병궤제、진치방법.방법 회고성분석수도의과대학대흥의원비창상성비파렬5례환자적림상자료,병결합상관문헌진행분석토론.결과 비창상성비파렬환자남성다견,평균년령대.해병병인교다,이혈액병、병독감염、국부염증화종류다견.발병궤제여비장증대、취성증가、응혈장애、비위치이상、격기강렬수축등유관.기학진교창상성비파렬곤난.치료이수술위주,부분환자야가행비수술치료.기예후여병인、년령유관.결론 비창상성비파렬병인교다,병이성비파렬점절대다수,림상진단곤난,치료이비절제술위주.
Objective To study the etiology,pathogenesis,diagnosis and treatment of non-traumatic splenic rupture.Method The clinical data of patients with atraumatic splenic rupture from our hospital were retrospectively analyzed,and the liferatures were reviewed.Results Most cases were male.The average age was high.The etiological factors were diverse,and the most common being blood diseases,virus infection,local inflammation and neoplasm.The pathogenesis is related to splenomegaly,increase in splenic fragility,altered haemostatic mechanisms,malposition of the spleen,and violent contraction of the diaphragm.It is more difficult to arrive at a diagnosis when compared with traumatic splenic rupture.Most patients required splenectomy,especially when the etiological factors were malignant blood diseases or splenic tumors.Some patients received non-operative treatment.The prognosis was related to the etiological factors and age.Conclusions The etiological factors of non-traumatic splenic rupture were diverse,and pathological splenic rupture was most common.A preoperative diagnosis was difficult,and splenectomy was the most common treatment.