中国继续医学教育
中國繼續醫學教育
중국계속의학교육
CHINA CONTINUING MEDICAL EDUCATION
2015年
12期
8-9
,共2页
抗CCP抗体%RF%类风湿性关节炎%诊断价值
抗CCP抗體%RF%類風濕性關節炎%診斷價值
항CCP항체%RF%류풍습성관절염%진단개치
Anti CCP antibody%RF%Rheumatoid arthritis%Diagnosis value
目的：比较探讨抗CCP抗体和RF对类风湿性关节炎的诊断价值。方法选取2014年1月～2015年1月间我院收治的60例类风湿性关节炎患者作为患者组，并抽取同期到院健康体检的60例健康人群作为正常组，两组均于清晨静脉采血以进行抗CCP抗体和RF检测，计算比较两种检测方法的敏感度、特异性、阳性预测值、阴性预测值以及总符合率。结果在两组患者阳性检出率比较中，患者组在抗CCP抗体和RF检测中的阳性检出率均高于正常组，组间数据差异具有统计学意义（P＜0.05）；而两种检测方法敏感度等价值的比较中可见RF的敏感度略高于抗CCP抗体，但抗CCP抗体的特异性、阳性预测值、阴性预测值以及总符合率均高于RF，组间比较差异具有统计学意义（P＜0.05）。结论抗CCP抗体与RF检测对类风湿性关节炎均具有诊断价值，但RF更具敏感度，而抗CCP抗体的特异性检测更具价值，根据两者的不同，联合应用应对类风湿性关节炎的检测更具重要意义。
目的：比較探討抗CCP抗體和RF對類風濕性關節炎的診斷價值。方法選取2014年1月～2015年1月間我院收治的60例類風濕性關節炎患者作為患者組，併抽取同期到院健康體檢的60例健康人群作為正常組，兩組均于清晨靜脈採血以進行抗CCP抗體和RF檢測，計算比較兩種檢測方法的敏感度、特異性、暘性預測值、陰性預測值以及總符閤率。結果在兩組患者暘性檢齣率比較中，患者組在抗CCP抗體和RF檢測中的暘性檢齣率均高于正常組，組間數據差異具有統計學意義（P＜0.05）；而兩種檢測方法敏感度等價值的比較中可見RF的敏感度略高于抗CCP抗體，但抗CCP抗體的特異性、暘性預測值、陰性預測值以及總符閤率均高于RF，組間比較差異具有統計學意義（P＜0.05）。結論抗CCP抗體與RF檢測對類風濕性關節炎均具有診斷價值，但RF更具敏感度，而抗CCP抗體的特異性檢測更具價值，根據兩者的不同，聯閤應用應對類風濕性關節炎的檢測更具重要意義。
목적：비교탐토항CCP항체화RF대류풍습성관절염적진단개치。방법선취2014년1월～2015년1월간아원수치적60례류풍습성관절염환자작위환자조，병추취동기도원건강체검적60례건강인군작위정상조，량조균우청신정맥채혈이진행항CCP항체화RF검측，계산비교량충검측방법적민감도、특이성、양성예측치、음성예측치이급총부합솔。결과재량조환자양성검출솔비교중，환자조재항CCP항체화RF검측중적양성검출솔균고우정상조，조간수거차이구유통계학의의（P＜0.05）；이량충검측방법민감도등개치적비교중가견RF적민감도략고우항CCP항체，단항CCP항체적특이성、양성예측치、음성예측치이급총부합솔균고우RF，조간비교차이구유통계학의의（P＜0.05）。결론항CCP항체여RF검측대류풍습성관절염균구유진단개치，단RF경구민감도，이항CCP항체적특이성검측경구개치，근거량자적불동，연합응용응대류풍습성관절염적검측경구중요의의。
Objective To investigate the value of comparison of anti CCP antibody and RF in diagnosis of rheumatoid arthritis.MethodsFrom 2014 January to 2015 January in our hospital 60 cases of rheumatoid arthritis as a patient group, and selected the same period to healthy people 60 cases of hospital health examination as normal group, two groups were in the early morning of venous blood for anti CCP antibody and RF detection, calculation compared with two kinds of detection methods the sensitivity, speciifcity, positive predictive value, and negative predictive value and the total coincidence rate.Results In the two groups of patients with positive rate comparison, patients on anti CCP antibody and detection of RF positive rate was higher than that in the normal group, with statistically signiifcant differences between groups of data (P<0.05); while the RF visible value comparison of two methods for the detection sensitivity in the sensitivity is slightly higher than that of anti CCP antibody however, speciifcity, the positive predictive value of anti CCP antibody, negative predictive value and the total coincidence rate is higher than RF, statistically significant differences (P<0.05) data comparison.Conclusion the anti CCP antibody and RF detection were is valuable in the diagnosis of rheumatoid arthritis, but RF is more sensitive, and specific detection of anti CCP antibodies more value, according to the different application, combined detection of rheumatoid arthritis respond more important.
