CAJ | 학술논문

目的：探讨D-二聚体与急性脑梗死病情轻重程度与预后的关系。方法应用乳胶凝集法对98例脑梗死患者发病第1天及第3周时的血浆D-二聚体进行检测，确诊脑梗死98例为观察组；排除脑梗死87例为对照组；将观察组又按神经功能缺损程度分为轻型组27例，中型组50例，重型组21例。监测并比较分析各组之间的D-二聚体水平。结果脑梗死患者血浆中D-二聚体水平明显高于对照组（P<0.05），D-二聚体含量与病情严重程度呈正相关。结论 D-二聚体水平与急性脑梗死的预后存在一定的关系，可以作为评价脑梗死病变程度的重要指标。
목적：탐토D-이취체여급성뇌경사병정경중정도여예후적관계。방법응용유효응집법대98례뇌경사환자발병제1천급제3주시적혈장D-이취체진행검측，학진뇌경사98례위관찰조；배제뇌경사87례위대조조；장관찰조우안신경공능결손정도분위경형조27례，중형조50례，중형조21례。감측병비교분석각조지간적D-이취체수평。결과뇌경사환자혈장중D-이취체수평명현고우대조조（P<0.05），D-이취체함량여병정엄중정도정정상관。결론 D-이취체수평여급성뇌경사적예후존재일정적관계，가이작위평개뇌경사병변정도적중요지표。
Objective:To study the relationship between D-dimer and illness severity and prognosis of acute cerebral in-farction. Methods:The plasma D-dimer levels of 98 patients with cerebral infarction incidence were detected on the first day and latex agglutination method was used in the third week. 98 cases of confirmed cerebral infarction were used as the observation group while 87 cases of the rejected cerebral infarction as the control group. According to the degree of nervous function defect,observation group were divided into light group of 27 cases,medium group of 50 cases and severe group of 21 cases. D-dimer levels between groups were monitored and comparatively analysed. Results:Cerebral infarction patients had a significantly higher plasma D-dimer level than that of the control group(P<0. 05). D-dimer content was positively correlated with disease severity. Conclusion:D-dimer level has certain relations with the prognosis of acute cerebral infarc-tion,which can be used as an important indicator to evaluate the lesion degree of cerebral infarction .