CAJ | 학술논문

目的：探讨吸烟对老年男性肺功能的影响。方法选择2013年1~12月在该院门诊就诊的183例老年男性患者进行肺功能检查，然后分为吸烟组89例[慢性阻塞性肺疾病（COPD）55例、非COPD 34例）]和非吸烟组94例（COPD 46例、非COPD 48例），将各组人群的肺功能结果进行比较。结果 COPD患者的通气功能和换气功能均受损，但吸烟组与非吸烟组患者相比，用力肺活量（FVC）、1秒用力呼气容积（FEV1）、FEV1/FVC 比值、用力呼气50%肺活量（FEF50%）、用力呼气75%肺活量（FEF75%）、最大呼气中期流量（MMEF）、弥散率（KCO）下降更明显，差异均有统计学意义（P＜0.05）。在非COPD 患者中，吸烟组与非吸烟组相比，小气道功能的 FEF50%、FEF75%、MMEF 和一氧化碳弥散量（TLCO）均有下降，且低于正常值，差异有统计学意义（P＜0.05）。同时，吸烟组的FVC、FEV1/FVC比值、肺泡通气量（VA）虽在正常范围内，但与非吸烟组对比有所下降，且差异有统计学意义（P＜0.05）。结论吸烟可导致患者通气功能及肺弥散功能损伤，同时吸烟COPD患者肺功能较非吸烟COPD患者下降更明显，并且非COPD吸烟患者的肺功能较非COPD非吸烟患者的肺功能也有下降，以小气道通气功能下降更明显。
목적：탐토흡연대노년남성폐공능적영향。방법선택2013년1~12월재해원문진취진적183례노년남성환자진행폐공능검사，연후분위흡연조89례[만성조새성폐질병（COPD）55례、비COPD 34례）]화비흡연조94례（COPD 46례、비COPD 48례），장각조인군적폐공능결과진행비교。결과 COPD환자적통기공능화환기공능균수손，단흡연조여비흡연조환자상비，용력폐활량（FVC）、1초용력호기용적（FEV1）、FEV1/FVC 비치、용력호기50%폐활량（FEF50%）、용력호기75%폐활량（FEF75%）、최대호기중기류량（MMEF）、미산솔（KCO）하강경명현，차이균유통계학의의（P＜0.05）。재비COPD 환자중，흡연조여비흡연조상비，소기도공능적 FEF50%、FEF75%、MMEF 화일양화탄미산량（TLCO）균유하강，차저우정상치，차이유통계학의의（P＜0.05）。동시，흡연조적FVC、FEV1/FVC비치、폐포통기량（VA）수재정상범위내，단여비흡연조대비유소하강，차차이유통계학의의（P＜0.05）。결론흡연가도치환자통기공능급폐미산공능손상，동시흡연COPD환자폐공능교비흡연COPD환자하강경명현，병차비COPD흡연환자적폐공능교비COPD비흡연환자적폐공능야유하강，이소기도통기공능하강경명현。
Objective To discuss how smoking affects elderly smokers′pulmonary function. Methods The pulmonary function test was performed on 183 elderly smokers in the outpatient clinic from January ,2013 to December,2013. Divided them into smoking group(n=89),chronic obstructive pulmonary disease(COPD) group(n=55),non-COPD group(n=34),and non-smoker group(n=94,in which COPD=46,non-COPD=48). Compared pulmonary function results among all the groups. Results COPD patients′ventilation function and gas exchange function were damaged ,among which Smokers′forced vital capacity (FVC),one second forced expiration capacity (FEV1),one second rate (FEV1/FVC),50%forced expiration flow (FEF 50%),75%forced expi ration flow(FEF 75%),and maximum expiration flow(MMEF) declined more obviously than non-smokers′,differences showing statistical significance(P<0.05). Smokers′,among non-COPD patients,FEF 50%,FEF 75%and MMEF declined to under normal value comparing to non-smokers′,differences showing statistical significance(P<0.05). Meanwhile,non-COPD smoking group′s FVC, FEV1/FVC,and alveolar ventilation(VA) declined comparing to non-smokers′even though they were within normal limits, differences showing statistical significance(P<0.05). Conclusion Smoking can cause patients′ventilation function and gas ex-change function damage. Smoking COPD patients′pulmonary function declines more obviously than non-smoking COPD patients′. Non-smoking COPD patients′pulmonary function declines more obviously than non-smoking non-COPD patients′,especially small airway ventilation function.