CAJ | 학술논문

为了解海南石斛(Dendrobium hainanenseRolfe)的化学成分，采用色谱技术从海南石斛茎叶中分离得到14个化合物，经波谱分析分别鉴定为：2,6-二甲氧基对苯醌(1)、(+)-dehydrovomifoliol (2)、blumenol A (3)、2,7-二羟基-3,4-二甲氧基-9,10-二氢菲(4)、2,7-二羟基-3,4-二甲氧基菲(5)、3,7-二羟基-2,4-二甲氧基菲(6)、3-羟基-2,4,7-三甲氧基-9,10-二氢菲(7)、3-羟基-2,4,7-三甲氧基菲(8)、3,4,7-三羟基-2-甲氧基菲(9)、3,7-二羟基-2,4-二甲氧基-9,10-二氢菲(10)、(+)-lyoniresinol (11)、丁香脂素(12)、denchrysan A (13)和nobilone (14)。这些化合物均为首次从海南石斛中分离得到。活性测试结果表明化合物4~6、8~9、11和14对乙酰胆碱酯酶有抑制活性。
위료해해남석곡(Dendrobium hainanenseRolfe)적화학성분，채용색보기술종해남석곡경협중분리득도14개화합물，경파보분석분별감정위：2,6-이갑양기대분곤(1)、(+)-dehydrovomifoliol (2)、blumenol A (3)、2,7-이간기-3,4-이갑양기-9,10-이경비(4)、2,7-이간기-3,4-이갑양기비(5)、3,7-이간기-2,4-이갑양기비(6)、3-간기-2,4,7-삼갑양기-9,10-이경비(7)、3-간기-2,4,7-삼갑양기비(8)、3,4,7-삼간기-2-갑양기비(9)、3,7-이간기-2,4-이갑양기-9,10-이경비(10)、(+)-lyoniresinol (11)、정향지소(12)、denchrysan A (13)화nobilone (14)。저사화합물균위수차종해남석곡중분리득도。활성측시결과표명화합물4~6、8~9、11화14대을선담감지매유억제활성。
The aim was to understand the chemical constituents ofDendrobium hainanense. Fourteen compounds were isolated from its aerial parts by means of chromatographic techniques. On the basis of spectral data, they were identiifed as: 2,6-dimethoxy-p-benzoquinone (1), (+)-dehydrovomifoliol (2), blumenol A (3), erianthridin (4), nudol (5), 3,7-dihydroxy-2,4-dimethoxy-phenanthrene (6),3-hydroxy-2,4,7-trimethoxy-9,10-dihydro- phenanthrene (7), 3-hydroxy-2,4,7-trimethoxy-9,10-dihydro-phenanthrene (8), 3,4,7-trihydroxy-2-methoxy-phenanthrene (9), 3,7-dihydroxy-2,4-dimethoxy-9,10-dihydro-phenanthrene (10), (+)-lyoniresinol (11), (+)- syringaresinol (12), denchrysan A (13) and nobilone (14). All compounds were isolated fromD. hainenensefor the ifrst time. Compounds4–6,8–9,11 and14 showed weak inhibitory activity against acetylcholinesterase.