CAJ | 학술논문

超氧化物歧化酶（ SOD）是重要的抗氧化酶，参与活性氧的代谢以调节机体氧化与抗氧化之间的平衡。幽门螺杆菌（ Hp）感染为胃癌的高危因素之一，可通过慢性炎症促使大量活性氧形成，进而造成DNA损伤，增加罹患胃癌的风险。SOD表达与胃癌的发病风险、转移以及预后有关，针对SOD的研究可为胃癌的防治提供帮助。
초양화물기화매（ SOD）시중요적항양화매，삼여활성양적대사이조절궤체양화여항양화지간적평형。유문라간균（ Hp）감염위위암적고위인소지일，가통과만성염증촉사대량활성양형성，진이조성DNA손상，증가리환위암적풍험。SOD표체여위암적발병풍험、전이이급예후유관，침대SOD적연구가위위암적방치제공방조。
Superoxide dismutase( SOD)is an important antioxidant enzyme,and plays an important role in active oxygen metabolism to regulate the balance between oxidation and anti-oxidation. Helicobacter pylori( Hp)infection,one of the risk factors of gastric cancer,can induce large number of reactive oxygen species by chronic inflammation,which causes DNA damage and high risk of gastric cancer. Expression of SOD is correlated with risk,metastasis and prognosis of gastric cancer. Studies on SOD can provide great help for the prevention and treatment of gastric cancer.