国际检验医学杂志
國際檢驗醫學雜誌
국제검험의학잡지
INTERNATIONAL JOURNAL OF LABORATORY MEDICINE
2015年
10期
1419-1420
,共2页
急性脑梗死%白细胞介素%肿瘤坏死因子-α
急性腦梗死%白細胞介素%腫瘤壞死因子-α
급성뇌경사%백세포개소%종류배사인자-α
acute cerebral infarction%interleukin%tumor necrosis factor-α
目的：探讨急性脑梗死患者血清白细胞介素‐1β（IL‐1β）、白细胞介素‐8（IL‐8）及肿瘤坏死因子‐α（T N F‐α）水平的变化及其临床意义。方法用酶联免疫吸附测定（ELISA）检测187例急性脑梗死患者血清IL‐1β、IL‐8及TNF‐α的水平，并与150例健康者进行比较。结果急性脑梗死患者不同梗死体积亚组血清IL‐1β、IL‐8及T N F‐α水平均高于对照组，差异均有统计学意义（P＜0．05），并且随梗死体积的增加而增高。结论急性脑梗死患者血清IL‐1β、IL‐8及TNF‐α水平增高，其升高的程度与梗死体积密切相关，可用于其病情评估、疗效监测和预后判断。
目的：探討急性腦梗死患者血清白細胞介素‐1β（IL‐1β）、白細胞介素‐8（IL‐8）及腫瘤壞死因子‐α（T N F‐α）水平的變化及其臨床意義。方法用酶聯免疫吸附測定（ELISA）檢測187例急性腦梗死患者血清IL‐1β、IL‐8及TNF‐α的水平，併與150例健康者進行比較。結果急性腦梗死患者不同梗死體積亞組血清IL‐1β、IL‐8及T N F‐α水平均高于對照組，差異均有統計學意義（P＜0．05），併且隨梗死體積的增加而增高。結論急性腦梗死患者血清IL‐1β、IL‐8及TNF‐α水平增高，其升高的程度與梗死體積密切相關，可用于其病情評估、療效鑑測和預後判斷。
목적：탐토급성뇌경사환자혈청백세포개소‐1β（IL‐1β）、백세포개소‐8（IL‐8）급종류배사인자‐α（T N F‐α）수평적변화급기림상의의。방법용매련면역흡부측정（ELISA）검측187례급성뇌경사환자혈청IL‐1β、IL‐8급TNF‐α적수평，병여150례건강자진행비교。결과급성뇌경사환자불동경사체적아조혈청IL‐1β、IL‐8급T N F‐α수평균고우대조조，차이균유통계학의의（P＜0．05），병차수경사체적적증가이증고。결론급성뇌경사환자혈청IL‐1β、IL‐8급TNF‐α수평증고，기승고적정도여경사체적밀절상관，가용우기병정평고、료효감측화예후판단。
Objective To explore the changes and clinical significance of the serum concentrations of serum IL‐1β,IL‐8 and TNF‐αin patients with acute cerebral infarction .Methods Serum concentrations of IL‐1β,IL‐8 and TNF‐αfrom 187 patients with acute cerebral infarction and 150 healthy donors were determined by enzyme linked immunosorbent assay (ELISA) .Results The serum levels of IL‐1β,IL‐8 and TNF‐αwere markedly higher in the 3 different infarct size subgroups than in the control group ,and the 3 indexes were statistically increased with increasing infarct size .Conclusion Serum levels of IL‐1β,IL‐8 and TNF‐αincreased markedly in patients with acute cerebral infarction ,which was closely related to infarct size ,and could be used as the indicators for severity assessment ,therapy monitoring and prognosis judgement in acute cerebral infarction patients .
