中南大学学报（英文版）
中南大學學報（英文版）
중남대학학보（영문판）
JOURNAL OF CENTRAL SOUTH UNIVERSITY OF TECHNOLOGY(ENGLISH EDITION)
2015年
6期
2081-2087
,共7页
许海峰%钟宏%王帅%李方旭
許海峰%鐘宏%王帥%李方旭
허해봉%종굉%왕수%리방욱
aldol condensation%one-pot synthesis%phase-transfer catalyst%aldehyde
One-pot synthesis of cyclic aldol tetramer anda,β-unsaturated aldol from C3?C8 linear aldehydes using phase-transfer catalyst (PTC), quaternary ammonium, combined with sodium hydroxide as catalysts was investigated. Butanal was subjected for detail investigations to study the effect of parameters. It was found that the selectivity of cyclic aldol tetramer depends greatly on the operating conditions of the reaction, especially the PTC/butanal molar ratio. The average selectivity of 2-hydroxy-6-propyl-l, 3, 5-triethyl-3-cyclohexene-1-carboxaldehyde (HPTECHCA) was 54.41% using tetrabutylammonium chloride combined with 14% (mass fraction) NaOH as catalysts at 60 °C for 2 h with a PTC-to-butanal molar ratio of 0.09:1. Pentanal was more likely to generate cyclic aldol tetramer compared with other aldehydes under the optimum experimental conditions. Recovery of the PTC through water washing followed by adding enough sodium hydroxide from the washings was also demonstrated.
