CAJ | 학술논문

目的：观察石氏针刺疗法配合口服益肾蠲痹丸治疗膝骨关节炎的临床疗效和安全性。方法：将120例膝骨关节炎患者随机分为2组，每组60例，分别采用石氏针刺疗法配合口服益肾蠲痹丸和传统针刺疗法治疗。于治疗前和治疗3周后，分别记录并比较2组患者膝关节疼痛视觉模拟评分（vsual analogue score，VAS）及西安大略和麦克马斯特大学（Western Ontario and McMaster Universities，WOMAC）量表积分；并在治疗期间观察有无与治疗相关的不良反应。结果：治疗3周后，3例患者脱落，其中石氏针刺疗法配合口服益肾蠲痹丸组脱落1例，传统针刺疗法组脱落2例。治疗前2组患者膝关节疼痛 VAS 评分及 WOMAC 量表积分比较，差异均无统计学意义[（7．14±1．14）分，（7．20±1．15）分，t ＝－0．180，P ＝0．858；（57．26±8．49）分，（56．36±8．76）分，t ＝0．404，P ＝0．688]。治疗3周后，2组患者膝关节疼痛 VAS 评分[（2．90±1．47）分，（3．83±1．51）分]及 WOMAC 量表积分[（25．69±5．31）分，（34．90±4．75）分]均较治疗前下降（t ＝11．559，P ＝0．000；t ＝9．505，P ＝0．000；t ＝13．319，P ＝0．000；t ＝9．627，P ＝0．000）；2组患者膝关节疼痛 VAS 评分下降幅度比较，差异无统计学意义[（4．18±1．95）分，（3．34±1．89）分，t ＝1．537，P ＝0．121]；石氏针刺疗法配合口服益肾蠲痹丸组膝关节 WOMAC 量表积分下降幅度大于传统针刺疗法组[（31．65±12．79）分，（21．86±12．22）分，t ＝2．830，P ＝0．006]。2组患者在治疗期间均未出现不良反应。结论：采用石氏针刺疗法配合口服益肾蠲痹丸和传统针刺疗法治疗 KOA，均能缓解膝关节疼痛，不良反应小；但在改善膝关节功能方面，石氏针刺配合口服益肾蠲痹丸优于传统针刺疗法，值得临床推广应用。目的：觀察石氏針刺療法配閤口服益腎蠲痺汍治療膝骨關節炎的臨床療效和安全性。方法：將120例膝骨關節炎患者隨機分為2組，每組60例，分彆採用石氏針刺療法配閤口服益腎蠲痺汍和傳統針刺療法治療。于治療前和治療3週後，分彆記錄併比較2組患者膝關節疼痛視覺模擬評分（vsual analogue score，VAS）及西安大略和麥剋馬斯特大學（Western Ontario and McMaster Universities，WOMAC）量錶積分；併在治療期間觀察有無與治療相關的不良反應。結果：治療3週後，3例患者脫落，其中石氏針刺療法配閤口服益腎蠲痺汍組脫落1例，傳統針刺療法組脫落2例。治療前2組患者膝關節疼痛 VAS 評分及 WOMAC 量錶積分比較，差異均無統計學意義[（7．14±1．14）分，（7．20±1．15）分，t ＝－0．180，P ＝0．858；（57．26±8．49）分，（56．36±8．76）分，t ＝0．404，P ＝0．688]。治療3週後，2組患者膝關節疼痛 VAS 評分[（2．90±1．47）分，（3．83±1．51）分]及 WOMAC 量錶積分[（25．69±5．31）分，（34．90±4．75）分]均較治療前下降（t ＝11．559，P ＝0．000；t ＝9．505，P ＝0．000；t ＝13．319，P ＝0．000；t ＝9．627，P ＝0．000）；2組患者膝關節疼痛 VAS 評分下降幅度比較，差異無統計學意義[（4．18±1．95）分，（3．34±1．89）分，t ＝1．537，P ＝0．121]；石氏針刺療法配閤口服益腎蠲痺汍組膝關節 WOMAC 量錶積分下降幅度大于傳統針刺療法組[（31．65±12．79）分，（21．86±12．22）分，t ＝2．830，P ＝0．006]。2組患者在治療期間均未齣現不良反應。結論：採用石氏針刺療法配閤口服益腎蠲痺汍和傳統針刺療法治療 KOA，均能緩解膝關節疼痛，不良反應小；但在改善膝關節功能方麵，石氏針刺配閤口服益腎蠲痺汍優于傳統針刺療法，值得臨床推廣應用。
목적：관찰석씨침자요법배합구복익신견비환치료슬골관절염적림상료효화안전성。방법：장120례슬골관절염환자수궤분위2조，매조60례，분별채용석씨침자요법배합구복익신견비환화전통침자요법치료。우치료전화치료3주후，분별기록병비교2조환자슬관절동통시각모의평분（vsual analogue score，VAS）급서안대략화맥극마사특대학（Western Ontario and McMaster Universities，WOMAC）량표적분；병재치료기간관찰유무여치료상관적불량반응。결과：치료3주후，3례환자탈락，기중석씨침자요법배합구복익신견비환조탈락1례，전통침자요법조탈락2례。치료전2조환자슬관절동통 VAS 평분급 WOMAC 량표적분비교，차이균무통계학의의[（7．14±1．14）분，（7．20±1．15）분，t ＝－0．180，P ＝0．858；（57．26±8．49）분，（56．36±8．76）분，t ＝0．404，P ＝0．688]。치료3주후，2조환자슬관절동통 VAS 평분[（2．90±1．47）분，（3．83±1．51）분]급 WOMAC 량표적분[（25．69±5．31）분，（34．90±4．75）분]균교치료전하강（t ＝11．559，P ＝0．000；t ＝9．505，P ＝0．000；t ＝13．319，P ＝0．000；t ＝9．627，P ＝0．000）；2조환자슬관절동통 VAS 평분하강폭도비교，차이무통계학의의[（4．18±1．95）분，（3．34±1．89）분，t ＝1．537，P ＝0．121]；석씨침자요법배합구복익신견비환조슬관절 WOMAC 량표적분하강폭도대우전통침자요법조[（31．65±12．79）분，（21．86±12．22）분，t ＝2．830，P ＝0．006]。2조환자재치료기간균미출현불량반응。결론：채용석씨침자요법배합구복익신견비환화전통침자요법치료 KOA，균능완해슬관절동통，불량반응소；단재개선슬관절공능방면，석씨침자배합구복익신견비환우우전통침자요법，치득림상추엄응용。
Objective:To observe the clinical curative effect and safety of Shi’s acupuncture therapy combined with oral application of Yishen Juanbi Wan(益肾蠲痹丸,YSJBW)for the treatment of knee osteoarthritis(KOA).Methods:One hundred and twenty patients with KOA were randomly divided into 2 groups,60 cases in each group.The patients were treated with Shi’s acupuncture therapy combined with oral application of YSJBW(group A)and traditional acupuncture therapy(group B)respectively.The vsual analogue scores(VAS)and West-ern Ontario and McMaster Universities(WOMAC)scores were recorded and compared between the 2 groups before the treatment and after 3 -week treatment respectively.The treatment -related adverse reactions were observed during the treatment.Results:Three patients(1 case in group A and 2 cases in group B)dropped out after 3 -week treatment.There was no statistical difference in knee pain VAS scores and WOMAC scores between the 2 groups before the treatment(7.14 +/-1.14 vs 7.20 +/-1.15 points,t =-0.180,P =0.858;57.26 +/-8.49 vs 56.36 +/-8.76 points,t =0.404,P =0.688).The knee pain VAS scores(2.90 +/-1.47,3.83 +/-1.51 points)and WOMAC scores(25.69 +/-5.31,34.90 +/-4.75 points)decreased in the 2 groups after 3 -week treatment(t =11.559,P =0.000;t =9.505,P =0.000;t =13.319,P =0.000;t =9.627,P =0.000).There was no statistical difference in the descent degree of knee pain VAS scoresbetween the 2 groups(4.18 +/-1.95 vs 3.34 +/-1.89 points,t =1.537,P =0.121),while the knee -joint WOMAC scores decreased more significantly in group A compared to group B(31.65 +/-12.79 vs 21.86 +/-12.22 points,t =2.830,P =0.006).No adverse reac-tions were found in the 2 groups during the treatment period.Conclusion:Either Shi’s acupuncture therapy combined with oral application of YSJBW or the traditional acupuncture therapy can relieve knee pain with less adverse reactions in the treatment of KOA.However,the former surpasses the latter in improving knee function,so it is worthy of popularizing in clinic.