CAJ | 학술논문

目的：探索降钙素原（PCT）、C反应蛋白（CRP）和白细胞（WBC）计数联合检测在新生儿感染性肺炎诊断中的临床价值。方法以确诊的137例新生儿感染性肺炎患儿为研究对象，其中细菌感染组72例、非细菌感染组65例；同期出生的63例健康新生儿纳入对照组。检测各研究组新生儿PCT、CRP及WBC水平。结果细菌感染组PCT、CRP及WBC水平和阳性率均高于非细菌感染组和对照组（P＜0．05）。PCT对细菌感染所致新生儿感染性肺炎的诊断灵敏度、特异度均高于CRP与WBC ；三者联合检测可进一步提高诊断灵敏度。结论 PCT较CRP和WBC具有更高的诊断灵敏度和特异度；PCT、CRP和WBC联合检测对新生儿感染性肺炎的鉴别诊断及疗效评价具有重要的临床价值。
목적：탐색강개소원（PCT）、C반응단백（CRP）화백세포（WBC）계수연합검측재신생인감염성폐염진단중적림상개치。방법이학진적137례신생인감염성폐염환인위연구대상，기중세균감염조72례、비세균감염조65례；동기출생적63례건강신생인납입대조조。검측각연구조신생인PCT、CRP급WBC수평。결과세균감염조PCT、CRP급WBC수평화양성솔균고우비세균감염조화대조조（P＜0．05）。PCT대세균감염소치신생인감염성폐염적진단령민도、특이도균고우CRP여WBC ；삼자연합검측가진일보제고진단령민도。결론 PCT교CRP화WBC구유경고적진단령민도화특이도；PCT、CRP화WBC연합검측대신생인감염성폐염적감별진단급료효평개구유중요적림상개치。
Objective To explore the clinical value of combined detection of procalcitonin (PCT ) ,C reaction protein (CRP) and white blood cells (WBC) count in diagnosis of neonatal infectious pneumonia .Methods A total of 137 cases of neonatal infectious pneumonia ,including bacterial infection group of 72 cases and non‐bacterial infection group of 65 cases ,were selected .Another 63 healthy neonatus were enrolled as control group .Levels of PCT ,CRP and WBC were measured .Results Levels and positive rates of PCT ,CRP and WBC in bacterial infection group were significantly higher than the other two groups (P<0 .05) .The sensitivity and specificity of PCT were higher than CRP and WBC .The sensitivity of combined detection were further increased .Conclusion Diagnostic sensitivity and specificity of PCT could be higher than CRP and WBC .Combined detection of PCT ,CRP and WBC might be with important clinical value for the differential diagnosis of neonatal infectious pneumonia and observation of curative effect .