CAJ | 학술논문

目的：了解本院鲍曼不动杆菌（AB）临床分布及耐药性特征。方法对2012～2013年共计1190株AB临床分布特征、药敏实验结果进行回顾性分析。结果1190株AB主要分离自痰标本，主要分布于重症监护病房、神经外科和呼吸内科。AB对多数抗菌药物的耐药率达到60％～80％，其中对妥布霉素、哌拉西林／他唑巴坦和亚胺培南的耐药率上升最为显著，对头孢哌酮／舒巴坦的耐药率有所下降。结论 AB对多种抗菌药物耐药严重，且耐药性上升趋势明显。应加强耐药性监测，合理使用抗菌药物，防止耐药株的产生和流行。
목적：료해본원포만불동간균（AB）림상분포급내약성특정。방법대2012～2013년공계1190주AB림상분포특정、약민실험결과진행회고성분석。결과1190주AB주요분리자담표본，주요분포우중증감호병방、신경외과화호흡내과。AB대다수항균약물적내약솔체도60％～80％，기중대타포매소、고랍서림／타서파탄화아알배남적내약솔상승최위현저，대두포고동／서파탄적내약솔유소하강。결론 AB대다충항균약물내약엄중，차내약성상승추세명현。응가강내약성감측，합리사용항균약물，방지내약주적산생화류행。
Objective To study the clinical distribution and drug resistance of Acinetobacter baumannii (AB) .Methods Clinical distribution and drug resistance of 1 190 strains of AB ,isolated in 2012 and 2013 ,were retrospectively analyzed .Results Most of AB strains were isolated from sputum ,and mainly from Intensive Care Unit ,Department of Neurosurgery and Department of Re‐spiratory .Resistance rates of AB to most antimicrobial agents were 60% -80% .Resistance rate to tobramycin ,piperacillin/tazobac‐tam and imipenem was increased significantly .Resistance rate to cefoperazone/sulbactam was decreased .Conclusion Drug resist‐ance of AB might be serious ,with increasing tendency .