CAJ | 학술논문

目的：探讨D‐二聚体（D‐D）、肌钙蛋白 T （cTnT ）及心肌酶谱检测在急性心肌梗死（AMI）临床诊断中的价值。方法选取AMI患者36例（AMI组）和体检健康者20例（健康对照组）作为研究对象，检测两组血浆D‐D、cTnT、心肌酶谱水平及其灵敏度、特异度。结果 AMI组D‐D、cTnT、肌酸激酶（CK）、肌酸激酶同工酶MB（CK‐MB）、天门冬氨酸氨基转移酶（AST ）、乳酸脱氢酶（LDH）水平均明显高于健康对照组，差异均有统计学意义（P＜0．05）。AMI患者中，cTnT、D‐D、心肌酶谱的阳性率分别为91．67％、69．44％、66．67％，cTnT阳性率明显高于D‐D和心肌酶谱（P＜0．05）。血浆cTnT对AMI的诊断灵敏度和特异度明显高于D‐D和心肌酶谱（P＜0．05）。结论与D‐D和心肌酶谱相比，cTnT对AMI的诊断灵敏度和特异度更好，临床上可多项联合检测提高检测准确性。
목적：탐토D‐이취체（D‐D）、기개단백 T （cTnT ）급심기매보검측재급성심기경사（AMI）림상진단중적개치。방법선취AMI환자36례（AMI조）화체검건강자20례（건강대조조）작위연구대상，검측량조혈장D‐D、cTnT、심기매보수평급기령민도、특이도。결과 AMI조D‐D、cTnT、기산격매（CK）、기산격매동공매MB（CK‐MB）、천문동안산안기전이매（AST ）、유산탈경매（LDH）수평균명현고우건강대조조，차이균유통계학의의（P＜0．05）。AMI환자중，cTnT、D‐D、심기매보적양성솔분별위91．67％、69．44％、66．67％，cTnT양성솔명현고우D‐D화심기매보（P＜0．05）。혈장cTnT대AMI적진단령민도화특이도명현고우D‐D화심기매보（P＜0．05）。결론여D‐D화심기매보상비，cTnT대AMI적진단령민도화특이도경호，림상상가다항연합검측제고검측준학성。
Objective To investigate the value of D‐dimer (D‐D) ,cardiac troponin T(cTnT) and myocardial enzymogram detec‐tions in clinical diagnosis of acute myocardial infarction (AMI) .Methods 36 cases of AMI patients (AMI group) and 20 cases of healthy people (control group) were selected as study subjects .The plasma levels of D‐D ,cTnT and myocardial enzymogram of two groups were detected ,and the sensibility and specificity of these indexes were analyzed .Results The levels of D‐D ,cTnT ,CK ,CK‐MB ,AST and LDH in AMI group were significantly higher than those of control group (P<0 .05) .The positive rates of cTnT ,D‐D and myocardial enzymogram in AMI patients were 91 .67% ,69 .44% ,and 66 .67% ,respectively .The positive rate of cTnT was significantly higher than those of D‐D and myocardial enzymogram (P<0 .05) .Both of the diagnosis sensibility and specificity of plasma cTnT were significantly higher than those of D‐D and myocardial enzymogram (P<0 .05) .Conclusion Comparing with D‐D and myocardial enzymogram ,plasma cTnT has better diagnosis sensibility and specificity .Joint detection of kinds of indexes could improve the accuracy .