CAJ | 학술논문

目的：探讨酮替芬联合孟鲁司特钠对毛细支气管炎后喘息的临床疗效。方法：对78例毛细支气管炎治愈后近期又有喘息发作的患儿，随机分为两组，对照组急性发作时给予吸入β2受体激动剂及糖皮质激素等综合治疗，同时口服孟鲁司特钠，咳喘缓解后继续口服孟鲁司特钠，疗程3个月。观察组在对照组基础上加用1周酮替芬治疗。观察治疗1周内临床症状的改善情况、半年内喘息的发作情况。结果：观察组咳喘消退时间短于对照组，两组比较差异有统计学意义（P＜0.05）。两组半年内喘息发生率相比差异无统计学意义（P＞0.05）。结论：酮替芬联合孟鲁司特钠能明显改善小儿毛细支气管炎后喘息症状，缩短病程。
목적：탐토동체분연합맹로사특납대모세지기관염후천식적림상료효。방법：대78례모세지기관염치유후근기우유천식발작적환인，수궤분위량조，대조조급성발작시급여흡입β2수체격동제급당피질격소등종합치료，동시구복맹로사특납，해천완해후계속구복맹로사특납，료정3개월。관찰조재대조조기출상가용1주동체분치료。관찰치료1주내림상증상적개선정황、반년내천식적발작정황。결과：관찰조해천소퇴시간단우대조조，량조비교차이유통계학의의（P＜0.05）。량조반년내천식발생솔상비차이무통계학의의（P＞0.05）。결론：동체분연합맹로사특납능명현개선소인모세지기관염후천식증상，축단병정。
Objective To investigate the clinical efficacy of ketotifen combined with montelukast in wheezing after bronchiolitis .Methods In 78 cases of bronchiolitis were cured after recent and wheezing in children, were randomly divided into two groups, control group, acute attack given inhaled beta 2 agonists and corticosteroids therapy, and oral montelukast sodium, cough and asthma remission after continuous oral administration of montelukast sodium, period of treatment 3 month. The observation group in the control group based on the use of 1 weeks of ketotifen treatment. The episodes to observe the improvement within 1 weeks of treatment, clinical symptoms within six months of breathing.Results The observation group cough subsided time was shorter than the control group, there was significant difference between two groups (P <0.05). Two groups of six months breathing incidence rate had no significant difference (P>0.05).Conclusion Ketotifen combined with montelukast sodium can significantly improve the children with bronchiolitis wheezing after symptoms, shorten the course of disease.