中国CT和MRI杂志
中國CT和MRI雜誌
중국CT화MRI잡지
CHINESE JOURNAL OF CT AND MRI
2015年
6期
12-15
,共4页
郭志锐%高明勇%赵海%杨冠英
郭誌銳%高明勇%趙海%楊冠英
곽지예%고명용%조해%양관영
鼻咽癌%化放疗%DWI%MRI%转移性淋巴结
鼻嚥癌%化放療%DWI%MRI%轉移性淋巴結
비인암%화방료%DWI%MRI%전이성림파결
Nasopharyngeal Carcinoma%Radiotherapy%DWI%MRI%Metastatic Lymph Nodes
目的:临床应用弥散加权成像(DWI)于鼻咽癌转移性淋巴结化放疗中,并通过监测治疗过程中表观弥散系数(ADC)变化情况来评价DWI对患者化放疗的应用价值。方法选取本院经手术及病理证实的60例鼻咽癌患者进行研究,并采用化放疗治疗。分别于首次化疗前1天、第二次化疗前1天、首次放疗前1天、第15天放疗当日和第30次放疗当日及治疗结束1个月后采用MRI及DWI进行检查。结果(1)治疗前,淋巴结平均ADC值为(0.792±0.019)×10-3mm2/s明显低于正常舌肌ADC值(1.387±0.035)×10-3mm2/s,P<0.05;(2)随着治疗的进行,患者转移性淋巴结ADC值随之而不断上升,但第1-15次放疗期间上升最为显著;(3)经治疗后,患者残留淋巴结ADC值平均为(1.399±0.079)×10-3mm2/s较治疗前明显增高,P<0.05;但其与治疗后正常舌肌ADC值比较,P>0.05。结论通过采用DWI及MRI监测鼻咽癌转移性淋巴结患者化放疗治疗过程中ADC值变化,可有效评估临床疗效,从而为患者临床合理化治疗提供参考。
目的:臨床應用瀰散加權成像(DWI)于鼻嚥癌轉移性淋巴結化放療中,併通過鑑測治療過程中錶觀瀰散繫數(ADC)變化情況來評價DWI對患者化放療的應用價值。方法選取本院經手術及病理證實的60例鼻嚥癌患者進行研究,併採用化放療治療。分彆于首次化療前1天、第二次化療前1天、首次放療前1天、第15天放療噹日和第30次放療噹日及治療結束1箇月後採用MRI及DWI進行檢查。結果(1)治療前,淋巴結平均ADC值為(0.792±0.019)×10-3mm2/s明顯低于正常舌肌ADC值(1.387±0.035)×10-3mm2/s,P<0.05;(2)隨著治療的進行,患者轉移性淋巴結ADC值隨之而不斷上升,但第1-15次放療期間上升最為顯著;(3)經治療後,患者殘留淋巴結ADC值平均為(1.399±0.079)×10-3mm2/s較治療前明顯增高,P<0.05;但其與治療後正常舌肌ADC值比較,P>0.05。結論通過採用DWI及MRI鑑測鼻嚥癌轉移性淋巴結患者化放療治療過程中ADC值變化,可有效評估臨床療效,從而為患者臨床閤理化治療提供參攷。
목적:림상응용미산가권성상(DWI)우비인암전이성림파결화방료중,병통과감측치료과정중표관미산계수(ADC)변화정황래평개DWI대환자화방료적응용개치。방법선취본원경수술급병리증실적60례비인암환자진행연구,병채용화방료치료。분별우수차화료전1천、제이차화료전1천、수차방료전1천、제15천방료당일화제30차방료당일급치료결속1개월후채용MRI급DWI진행검사。결과(1)치료전,림파결평균ADC치위(0.792±0.019)×10-3mm2/s명현저우정상설기ADC치(1.387±0.035)×10-3mm2/s,P<0.05;(2)수착치료적진행,환자전이성림파결ADC치수지이불단상승,단제1-15차방료기간상승최위현저;(3)경치료후,환자잔류림파결ADC치평균위(1.399±0.079)×10-3mm2/s교치료전명현증고,P<0.05;단기여치료후정상설기ADC치비교,P>0.05。결론통과채용DWI급MRI감측비인암전이성림파결환자화방료치료과정중ADC치변화,가유효평고림상료효,종이위환자림상합이화치료제공삼고。
Objective Clinical application of diffusion-weighted imaging (DWI) in nasopharyngeal carcinoma metastatic lymph node radiotherapy in the treatment process and by monitoring the apparent diffusion coefficient (ADC) to evaluate changes in the value of radiotherapy in patients with DWI.Methods Select the hospital after surgery and pathology confirmed 60 cases of nasopharyngeal carcinoma patients were studied, and the use of radiotherapy. Respectively, one day before the first chemotherapy, the second one days before chemotherapy, one day before the first radiotherapy, radiotherapy day and the 15th day of the 30th day of radiotherapy and one month after the end of treatment using MRI and DWI checks.Results (1) Before treatment, the mean ADC value of lymph node (0.792±0.019)×10-3mm2/s ADC values were significantly lower than normal tongue (1.387±0.035)×10-3mm2/s, P <0.05; (2) with the treatment progresses, patients with metastatic lymph nodes attendant rising ADC value, but during the first 1 to 15 times the most significant increase in radiation; (3) after treatment, the residual lymph nodes in patients with average ADC value (1.399±0.079)×10-3mm2/s was significantly higher than before treatment, P<0.05; but after treatment compared with normal tongue ADC value, P>0.05.Conclusion Through the use of DWI and MRI monitoring of metastatic lymph nodes in patients with nasopharyngeal carcinoma radiotherapy ADC value change during treatment, which can effectively evaluate the clinical efficacy, which provides a reference for the clinical treatment of patients rationalization.