CAJ | 학술논문

目的：探讨极低出生体重儿（VLBWI）的围产高危因素、并发症及近期生长发育情况，以提高VLBWI诊治和生存质量。方法：选取2010年1月至2014年12月在珠海市出生，且于珠海市妇幼保健院儿保科体检的140例 VLBWI 按出生体重分为三组，比较其围产期情况、并发症、体重、身高（长）、头围、神经发育及视听功能。结果：本组140例VLBWI前6位围产高危因素是双胎、妊娠期高血压、胎膜早破、妊娠期内科相关疾病、体外受精－胚胎移植和子宫肿瘤，前6位的并发症是新生儿呼吸窘迫综合征、贫血、肺炎、电解质紊乱、窒息、高胆红素血症。患儿身高、体重、头围指标中一项异常者为28．6％，神经发育异常率、早产儿视网膜病变发生率、听力障碍发生率分别是28．1％、16．0％、7．75‰。结论：加强孕期保健和产前高危因素诊治是提高 VLBWI 生存质量的重要措施，定期体格是早期筛查患儿发育状况异常的有效措施。
목적：탐토겁저출생체중인（VLBWI）적위산고위인소、병발증급근기생장발육정황，이제고VLBWI진치화생존질량。방법：선취2010년1월지2014년12월재주해시출생，차우주해시부유보건원인보과체검적140례 VLBWI 안출생체중분위삼조，비교기위산기정황、병발증、체중、신고（장）、두위、신경발육급시은공능。결과：본조140례VLBWI전6위위산고위인소시쌍태、임신기고혈압、태막조파、임신기내과상관질병、체외수정－배태이식화자궁종류，전6위적병발증시신생인호흡군박종합정、빈혈、폐염、전해질문란、질식、고담홍소혈증。환인신고、체중、두위지표중일항이상자위28．6％，신경발육이상솔、조산인시망막병변발생솔、은력장애발생솔분별시28．1％、16．0％、7．75‰。결론：가강잉기보건화산전고위인소진치시제고 VLBWI 생존질량적중요조시，정기체격시조기사사환인발육상황이상적유효조시。
Objective: To explore the perinatal conditions,growth and development of very low birth weight infants (VLBWI) to improve the diagnosis and the life quality. Methods: The 140 patients with VLBWI born in Zhuhai in Child health division of Zhuhai maternity and child health hospital were divided into three groups according to birth weight from Jan 2010 to Dec 2014. The perinatal conditions,complication after birth,weight,height,head circumference,neuro developmental, visual and auditory were compared. Results: Among the 140 cases, twins, gestational hypertension, premature rupture of membranes,pregnancy-related medical disorders, in vitro fertilization-embryo transfer and uterine cancer were the high six risks of VLBWI, neonatal respiratory distress syndrome,anemia, pneumonia,electrolyte disorder,asphyxia,hyperbilirubinemia were the top six complications. One of the abnormal weight,height or head circumference in VLBWI was 28.6%. The neuro developmental abnormality rate was 28.1%. The incidence of retinopathy of prematurity was 16.0%. The hearing impairment rate was 7.75‰. Conclusion:Strengthen prenatal care and diagnosis of prenatal risk factors can improve the life quality of the VLBWI. The regular physical examination can be used as an effective measure for early screening of children with developmental abnormity.