CAJ | 학술논문

目的：探讨脑白质疏松症（LA）患者睡眠障碍的影响因素。方法选择90例符合 MRI 诊断标准的 LA 患者（LA组）和90例性别、年龄相匹配的正常老年人（NC 组）作为研究对象；通过询问病史调查血管危险因素，采用匹兹堡睡眠质量指数（PSQI）量表评定睡眠障碍情况，依据头颅 MRI 表现将 LA 组分为4个等级。结果 LA 组高血压和糖尿病发生率显著高于 NC 组（P <0.05），LA 组 PSQI 评分显著高于NC 组（P <0.01）。LA 组随着 LA 分级升高，PSQI 评分依次增高（P <0.05）。回归分析显示，年龄、高血压、糖尿病、蒙特利尔认知评估量表等与 LA 患者睡眠障碍有关。结论LA 患者存在睡眠障碍，与 LA 病变程度、认知损害、年龄、高血压、糖尿病等密切相关。
목적：탐토뇌백질소송증（LA）환자수면장애적영향인소。방법선택90례부합 MRI 진단표준적 LA 환자（LA조）화90례성별、년령상필배적정상노년인（NC 조）작위연구대상；통과순문병사조사혈관위험인소，채용필자보수면질량지수（PSQI）량표평정수면장애정황，의거두로 MRI 표현장 LA 조분위4개등급。결과 LA 조고혈압화당뇨병발생솔현저고우 NC 조（P <0.05），LA 조 PSQI 평분현저고우NC 조（P <0.01）。LA 조수착 LA 분급승고，PSQI 평분의차증고（P <0.05）。회귀분석현시，년령、고혈압、당뇨병、몽특리이인지평고량표등여 LA 환자수면장애유관。결론LA 환자존재수면장애，여 LA 병변정도、인지손해、년령、고혈압、당뇨병등밀절상관。
Objective To investigate the leukoaraiosis(LA)influencing factors of sleep disorder patients. Meth-ods 90 cases of LA patients which were conformed MRI diagnostic criteria were chosen as LA group,90 cases of normal old people which the gender and age were matched with LA group were chosen as NC group;by asking the medical history to inquirying blood vessel hazards;pittsburgh sleep quality index(PSQI)was adopted to evaluate the condition of sleep disorders,according to the performance MRI of skull to part LA group as four grades. Results In LA group,hypertension and diabetes incidence were significantly higher than that in group NC(P < 0. 05);LA group,PSQI score was significantly higher than that of NC group(P < 0. 01). LA group with the LA increasing grade,PSQI score increased(P < 0. 05). Regression analysis showed that age,hypertension,diabetes and MoCA were associated with LA in patients with sleep disorders. Conclusion Patients with LA have a sleep disorder, which is closely related with the degree of cognitive impairment,LA lesions,age,hypertension,diabetes etc.