CAJ | 학술논문

目的：对华法林抗凝治疗老年非瓣膜房颤患者的临床疗效观察，并探讨其抗凝强度。方法选取我院2012年5月～2013年3月收治的68例老年非瓣膜房颤患者，随机平均分为华法林观察组和阿司匹林对照组，对比两组患者中风及出血发生率。结果对照组患者发生缺血性中风概率为0%，观察组患者为2.9%，差异不明显（P＞0.05）；出血发生率观察组14.7%，对照组76.5%，两组都没有大出血发生，出血率差异显著（P＜0.05）。结论在对老年非瓣膜房颤患者的治疗中，华法林和阿司匹林都可以减少中风出血，但是华法林抗凝治疗效果显著，临床上要对其抗凝强度予以重视，减少轻度出血的发生。
목적：대화법림항응치료노년비판막방전환자적림상료효관찰，병탐토기항응강도。방법선취아원2012년5월～2013년3월수치적68례노년비판막방전환자，수궤평균분위화법림관찰조화아사필림대조조，대비량조환자중풍급출혈발생솔。결과대조조환자발생결혈성중풍개솔위0%，관찰조환자위2.9%，차이불명현（P＞0.05）；출혈발생솔관찰조14.7%，대조조76.5%，량조도몰유대출혈발생，출혈솔차이현저（P＜0.05）。결론재대노년비판막방전환자적치료중，화법림화아사필림도가이감소중풍출혈，단시화법림항응치료효과현저，림상상요대기항응강도여이중시，감소경도출혈적발생。
Objective The anticoagulation of warfarin in the treatment of elderly non clinical observation of patients with valvular atrial ifbrillation, and investigate the anticoagulant intensity.MethodsWe selected 68 cases of senile non valvular atrial ifbrillation patients in our hospital from 2012 May to 2013 March were randomly divided into the control group, the average for warfarin and aspirin in observation group, compared two groups of patients with stroke and bleeding rate.Results Patients in the control group the probability of occurrence of ischemic stroke was 0%, patients in the observation group was 2.9%, the difference was not signiifcant (P>0.05); Bleeding rate of the observation group 14.7%, control group 76.5%, two groups had no major bleeding, bleeding rate was significant difference (P<0.05).ConclusionIn the treatment of elderly patients with non valvular atrial ifbrillation, Hua Falin and aspirin can reduce hemorrhagic stroke, but significant therapeutic effect of anticoagulation clinic Hua Falin, to give attention to the intensity of anticoagulation, reduce the occurrence of mild hemorrhage.