CAJ | 학술논문

目的：探究类风湿关节炎患者应用硫酸羟氯喹治疗的临床效果与特点。方法研究对象是2013年5月～2014年7月期间从我院接收并治疗的类风湿性关节炎患者中随机性抽取的100例，并进行回顾性试验研究，分为对照和研究两组各50例。对照组患者使用的是甲氨蝶呤治疗；研究组在甲氨蝶呤治疗基础上加用硫酸羟氯喹治疗。结果通过不同方法治疗后12个月，研究组患者关节压痛数、晨僵时间、关节肿胀数、ESR与CRP等指标均优于对照组，效果显著（P＜0.05）。结论针对类风湿关节炎加用硫酸羟氯喹治疗，效果较好。
목적：탐구류풍습관절염환자응용류산간록규치료적림상효과여특점。방법연구대상시2013년5월～2014년7월기간종아원접수병치료적류풍습성관절염환자중수궤성추취적100례，병진행회고성시험연구，분위대조화연구량조각50례。대조조환자사용적시갑안접령치료；연구조재갑안접령치료기출상가용류산간록규치료。결과통과불동방법치료후12개월，연구조환자관절압통수、신강시간、관절종창수、ESR여CRP등지표균우우대조조，효과현저（P＜0.05）。결론침대류풍습관절염가용류산간록규치료，효과교호。
Objective To explore the clinical effect and characteristics of hydroxychloroquinein patients with rheumatoid arthritis treated with sulfuric acid.Methods The research object is during the period from 2013 May to 2014 July in our hospital and 100 cases received from randomness extraction of rheumatoid arthritis patients in treatment, and a retrospective pilot study, divided into control and study the two group with 50 cases in each group. The control group patients are using methotrexate therapy; research group in methotrexate therapy plus hydroxychloroquine sulfate treatment.Results 12 months after treatment by different methods, the study group patients tender joint count, time of morning stiffness, swollen joint count, ESR and CRP was significantly better than the control group, signiifcant effect (P<0.05).Conclusion In the treatment of hydroxychloroquine sulfate, rheumatoid arthritis and the effect is good, worthy of promotion.