CAJ | 학술논문

目的：了解重症监护病房(ICU)患者感染病原菌分布特点及耐药情况，为控制医院感染及临床选用抗菌药物治疗提供依据。方法：分析2011年12月-2014年12月I C U患者送检的各类标本中分离出的病原菌，进行病原菌耐药性分析。结果：分离出病原菌363株，标本来源中痰液阳性标本居首位，占77.4%；病原菌仍以革兰阴性杆菌为主，占69.7%，革兰阳性球菌占6.9%，真菌占总构成比23.4%。肺炎克雷白杆菌和大肠埃希菌产超广谱β-内酰胺酶(ESBLs)检出率分别61.2%和75%，耐甲氧西林葡萄球菌(MRSA)检出率为48.5%。结论：ICU为医院感染高发科室，病原菌仍以革兰阴性杆菌为主，坚持细菌耐药性监测，对ICU患者感染的诊治具有重要指导意义。
목적：료해중증감호병방(ICU)환자감염병원균분포특점급내약정황，위공제의원감염급림상선용항균약물치료제공의거。방법：분석2011년12월-2014년12월I C U환자송검적각류표본중분리출적병원균，진행병원균내약성분석。결과：분리출병원균363주，표본래원중담액양성표본거수위，점77.4%；병원균잉이혁란음성간균위주，점69.7%，혁란양성구균점6.9%，진균점총구성비23.4%。폐염극뢰백간균화대장애희균산초엄보β-내선알매(ESBLs)검출솔분별61.2%화75%，내갑양서림포도구균(MRSA)검출솔위48.5%。결론：ICU위의원감염고발과실，병원균잉이혁란음성간균위주，견지세균내약성감측，대ICU환자감염적진치구유중요지도의의。
Objective To investigate pathogen distribution and antimicrobial resistance in the intensive care unit (ICU) for the contro lof hospital infection and guidance of antibiotic clinical use of drug therapy.Methods From December 2011-December2014. ICU patients for all kinds of specimens in isolated pathogens, pathogenic bacteria drug resistance analysis.Results 363 pathogens were isolated.Sputum-positive samples ranked the first and accounted for 77.4%;pathogenic Gram-negative bacil i were stil dominated, accounted for 69.7%and Gram-positivecocciaccounted for 6.9%,fungiaccounted for 23.4% of the totalcomposition; Pneumonia Cray white Campylobacter and Escherichia coliultra-extended-spectrumβ-lactamases (ESBLs) had a detection rate of 61.2% and 75%, methicillin-resistant Staphylococcus aureus (MRSA) had a detection rate of 48.5%. Conclusion The rate of hospital infection was high in ICU. The pathogens were mainly Gram-negative bacteria. Bacterial resistance surveillance in ICU patients would be helpful for hospital-acquired infection diagnosis and treatment.