CAJ | 학술논문

目的：亚砷酸为主方案治疗急性早幼粒细胞白血病的临床效果。方法选择初诊患者125例分为亚砷酸+高三尖杉酯碱组、单独亚砷酸组、亚砷酸+其它化疗药物组，进行比较。结果前组较后两组完全缓解率比较，差异有统计学意义（P＜0.05）。前组较后两组生存率比较差异有统计学意义（P＜0.05）。结论亚砷酸与高三尖杉酯碱联合诱导方案能够显著提高初诊急性早幼粒细胞白血病完全缓解率。
목적：아신산위주방안치료급성조유립세포백혈병적림상효과。방법선택초진환자125례분위아신산+고삼첨삼지감조、단독아신산조、아신산+기타화료약물조，진행비교。결과전조교후량조완전완해솔비교，차이유통계학의의（P＜0.05）。전조교후량조생존솔비교차이유통계학의의（P＜0.05）。결론아신산여고삼첨삼지감연합유도방안능구현저제고초진급성조유립세포백혈병완전완해솔。
Objective To study the arsenic acid as the main solution for use in acute promyelocytic leukemia clinical effect.Methods Divided 26 patients into arsenous acid + three pointed cedar ester base group, the separate arsenite group, arsenic acid + other chemotherapy drugs group.Results The former group than in the two groups after complete remission rate comparison, the difference was statistically significant (P<0.05). Before the group later survival compared the two groups was statistically signiifcant difference (P<0.05).Conclusion Arsenous acid with Homobarringtonie base joint induction programme can improve both the acute myelocytic leukemia complete response rate signiifcantly.