浙江预防医学
浙江預防醫學
절강예방의학
ZHEJIANG JOURNAL OF PREVENTIVE MEDICINE
2015年
6期
556-560
,共5页
孕妇%新生儿%脐带血%汞水平%马鲛鱼
孕婦%新生兒%臍帶血%汞水平%馬鮫魚
잉부%신생인%제대혈%홍수평%마교어
Pregnant women%Newborn%Umbilical cord blood%Mercury exposure%Pan -fried mackerel
目的：了解舟山群岛新生儿脐带血汞暴露水平及影响因素。方法选择2012年6月—2013年7月进行围产保健并住院分娩的舟山户籍孕产妇及其新生儿为研究对象，对孕产妇全血和新生儿脐带血进行汞含量检测，问卷调查新生儿家庭社会环境与健康状况。结果共检测3052名孕妇全血及其新生儿脐带血汞水平，孕妇血汞平均为（5．33±3．69）μg／kg，中位数为4．63μg／kg，P25～P75为2．8～8．2μg／kg。新生儿脐带血汞含量平均为（7．72±4．87）μg／kg，中位数为7．31μg／kg，P25～P75为4．7～11．2μg／kg。单因素分析提示新生儿脐血汞与母亲孕期吃马鲛鱼有关联（OR ＝1．79，P ＜0．01），而与新生儿性别，母亲孕期补维生素、补钙、补铁、修补牙齿个数，母亲经常使用皮肤增白化妆品，孕期每月吃鱼及海产品次数及父亲每天吸烟、家庭月平均收入、在本地居住时间等均无关联。经多因素 Logistic 回归分析显示，脐血汞值与母亲孕期吃马鲛鱼存在关联（OR ＝1．96，P＜0．01）。结论舟山地区新生儿脐带血汞量水平较高，孕妇血汞值与脐血汞值相关，孕妇进食马鲛鱼是新生儿脐带血暴露水平的影响因素，有待进一步研究证实。
目的：瞭解舟山群島新生兒臍帶血汞暴露水平及影響因素。方法選擇2012年6月—2013年7月進行圍產保健併住院分娩的舟山戶籍孕產婦及其新生兒為研究對象，對孕產婦全血和新生兒臍帶血進行汞含量檢測，問捲調查新生兒傢庭社會環境與健康狀況。結果共檢測3052名孕婦全血及其新生兒臍帶血汞水平，孕婦血汞平均為（5．33±3．69）μg／kg，中位數為4．63μg／kg，P25～P75為2．8～8．2μg／kg。新生兒臍帶血汞含量平均為（7．72±4．87）μg／kg，中位數為7．31μg／kg，P25～P75為4．7～11．2μg／kg。單因素分析提示新生兒臍血汞與母親孕期喫馬鮫魚有關聯（OR ＝1．79，P ＜0．01），而與新生兒性彆，母親孕期補維生素、補鈣、補鐵、脩補牙齒箇數，母親經常使用皮膚增白化妝品，孕期每月喫魚及海產品次數及父親每天吸煙、傢庭月平均收入、在本地居住時間等均無關聯。經多因素 Logistic 迴歸分析顯示，臍血汞值與母親孕期喫馬鮫魚存在關聯（OR ＝1．96，P＜0．01）。結論舟山地區新生兒臍帶血汞量水平較高，孕婦血汞值與臍血汞值相關，孕婦進食馬鮫魚是新生兒臍帶血暴露水平的影響因素，有待進一步研究證實。
목적：료해주산군도신생인제대혈홍폭로수평급영향인소。방법선택2012년6월—2013년7월진행위산보건병주원분면적주산호적잉산부급기신생인위연구대상，대잉산부전혈화신생인제대혈진행홍함량검측，문권조사신생인가정사회배경여건강상황。결과공검측3052명잉부전혈급기신생인제대혈홍수평，잉부혈홍평균위（5．33±3．69）μg／kg，중위수위4．63μg／kg，P25～P75위2．8～8．2μg／kg。신생인제대혈홍함량평균위（7．72±4．87）μg／kg，중위수위7．31μg／kg，P25～P75위4．7～11．2μg／kg。단인소분석제시신생인제혈홍여모친잉기흘마교어유관련（OR ＝1．79，P ＜0．01），이여신생인성별，모친잉기보유생소、보개、보철、수보아치개수，모친경상사용피부증백화장품，잉기매월흘어급해산품차수급부친매천흡연、가정월평균수입、재본지거주시간등균무관련。경다인소 Logistic 회귀분석현시，제혈홍치여모친잉기흘마교어존재관련（OR ＝1．96，P＜0．01）。결론주산지구신생인제대혈홍량수평교고，잉부혈홍치여제혈홍치상관，잉부진식마교어시신생인제대혈폭로수평적영향인소，유대진일보연구증실。
Objective To investigate the mercury exposure level in cord blood of neonatal in Zhoushan Islands and to analyze the related factors,in order to provide scientific basis for relevant prevention and control measures.Methods From June 201 2 to July 201 3,peripheral blood and umbilical cord blood samples were collected in local women who delivered their babies in Zhoushan Islands.Questionnaire survey and mercury exposure test were performed.Results 3 052 maternal blood and neonatal umbilical cord blood samples were tested,and the mean,median,P25 and P75 of the maternal blood mercury were 5.33 ±3.69,4.63,2.8 and 8.2 μg/kg respectively.And the mean,median,P25 and P75 of the cord blood mercury were 7.72 ±4.87,7.31 ,4.7 and 1 1 .2 μg/kg.Single factor analysis showed that the neonatal umbilical cord blood mercury levels were associated the intake of pan -fried mackerel during pregnancy (OR =1 .79,P <0.01 ).No association was found with the sex of newborn,the intake of iron,calcium,and vitamin during pregnancy,the number of mending tooth,the use of whitening cosmetics,the intake of fish and seafood,father's smoking,the average family income and residence time.Multivariate Logistic regression analysis showed that the neonatal umbilical cord blood mercury levels were associated the intake of pan -fried mackerel during pregnancy (OR =1 .96,P <0.01 ).Conclusion Mercury levels in cord blood in Zhoushan area are detected at a high level;the intake of pan -fried mackerel could be one of the major sources of mercury accumulation in neonates.There is an association between the mercury levels of maternal blood and neonatal umbilical cord blood.
