CAJ | 학술논문

目的探讨扩张器包膜对自体异位移植后兔肋软骨生物力学性能的影响.方法在10只3月龄新西兰大白兔背部脊柱两侧对称埋置15 ml扩张器各4枚,持续扩张1个月后,取出扩张器,一侧去除扩张器包膜为去包膜组,一侧保留扩张器包膜为带包膜组,同时取右侧第7、8肋软骨,去除肋软骨膜后一分为二,分别放置于背部对称扩张囊腔内,分别于术后4、8周取左右对称部位的肋软骨,进行组织学观察.根据试验机要求制成相应大小标准试件进行生物力学测试,对测试结果进行统计学分析处理.结果 8周后,平均极限抗拉强度:去包膜组为(4.954+2.8) MPa,带包膜组为(2.939+0.842) MPa;平均压缩强度:去包膜组为(58.74±13.77) MPa,带包膜组为(47.61±11.41) MPa,去包膜组的抗拉强度及压缩强度均高于带包膜组,差异均有统计学意义(P＜0.05),表明去包膜组肋软骨各项生物力学性能优于带包膜组.结论去除扩张器包膜对移植后肋软骨生物力学性能的保持优于保留扩张器包膜组.
목적 탐토확장기포막대자체이위이식후토륵연골생물역학성능적영향.방법 재10지3월령신서란대백토배부척주량측대칭매치15 ml확장기각4매,지속확장1개월후,취출확장기,일측거제확장기포막위거포막조,일측보류확장기포막위대포막조,동시취우측제7、8륵연골,거제륵연골막후일분위이,분별방치우배부대칭확장낭강내,분별우술후4、8주취좌우대칭부위적륵연골,진행조직학관찰.근거시험궤요구제성상응대소표준시건진행생물역학측시,대측시결과진행통계학분석처리.결과 8주후,평균겁한항랍강도:거포막조위(4.954+2.8) MPa,대포막조위(2.939+0.842) MPa;평균압축강도:거포막조위(58.74±13.77) MPa,대포막조위(47.61±11.41) MPa,거포막조적항랍강도급압축강도균고우대포막조,차이균유통계학의의(P＜0.05),표명거포막조륵연골각항생물역학성능우우대포막조.결론 거제확장기포막대이식후륵연골생물역학성능적보지우우보류확장기포막조.
Objective To explore the effect of the expanded capsule on biomechanics of the transplanted autologous costal cartilage.Methods Ten New Zealand white rabbits aged 3 months were involved and four 15 ml tissue expanders were implanted symmetrically on the back of each rabbit.After 1 month,expanded capsules were removed (experimental group) on the left side and were reserved (control group) on the right side.Meanwhile,the 6th and 7th costal cartilage without the perichondrium were taken out and each cartilage was divided into two pieces and put under the expanded capsule symmetrically.The cartilage at the upper sides and lower sides were taken out at 4 weeks and 8 weeks later,respectively.All the cartilages were sculptured for the demand of the machine text.The tension and compression property of the cartilages were assessed by the material testing machine(Instron 5967) and the results were analyzed statistically.Results 8 weeks lateral,the average ultimate tension strength was (4.954 + 2.8) MPa in experimental group and (2.939 + 0.842) MPa in control group.The average compressive strength was (58.74 ± 13.77) MPa in experimental group,and(47.61 ± 11.41) MPa in control group.The biomechanics property of the cartilages in the experimental group is better than the control group,and the differences were statistically significant.Conclusions Removing the expanded capsule is benefical to maintain the biomechanics of autologous costal cartilage.