CAJ | 학술논문

目的：探讨采用左氧氟沙星四联方案在治疗幽门螺杆菌(Hp)中的应用及疗效。方法幽门螺杆菌患者共46例，按照随机的原则将其分为对照组和观察组，各23例，其中对照组采用传统的三联疗法进行治疗，观察组患者采用左氧氟沙星四联方案进行治疗，治疗后对两组患者临床疗效进行对比观察，应用活检黏膜快速尿素酶试验法进行检查，根据试验结果判定Hp是否根除。结果治疗后试验判定结果显示，对照组Hp根除率为65.2%，观察组为87.0%，两组间对比差异具有统计学意义(P<0.05)。结论在幽门螺杆菌的治疗过程中采用左氧氟沙星四联方案进行治疗可显著改善患者临床症状，提高治愈率，同时副作用少，值得在临床上进行推广和应用。
목적：탐토채용좌양불사성사련방안재치료유문라간균(Hp)중적응용급료효。방법유문라간균환자공46례，안조수궤적원칙장기분위대조조화관찰조，각23례，기중대조조채용전통적삼련요법진행치료，관찰조환자채용좌양불사성사련방안진행치료，치료후대량조환자림상료효진행대비관찰，응용활검점막쾌속뇨소매시험법진행검사，근거시험결과판정Hp시부근제。결과치료후시험판정결과현시，대조조Hp근제솔위65.2%，관찰조위87.0%，량조간대비차이구유통계학의의(P<0.05)。결론재유문라간균적치료과정중채용좌양불사성사련방안진행치료가현저개선환자림상증상，제고치유솔，동시부작용소，치득재림상상진행추엄화응용。
Objective To investigate application and curative effect of levofloxacin quadruple scheme in the treatment of helicobacter pylori (Hp).Methods A total of 46 patients with helicobacter pylori were randomly divided into control group and observation group, and each group contained 23 cases. The control group received traditional triple therapy for treatment, and the observation group received levofloxacin quadruple scheme for treatment. Clinical effects of the two groups were comparatively observed, and biopsy mucosal rapid urease test was applied in examination. Hp eradication was judged by examination results.Results The examination results after treatment showed the Hp eradication rate in the control group as 65.2%, and that in the observation group as 87.0%. The difference between the two groups had statistical significance (P<0.05).Conclusion Implement of levofloxacin quadruple scheme in the treatment of helicobacter pylori can remarkably improve patients’ clinical symptoms and increase cure rate, with few side effects. This method is worthy of clinical promotion and application.