CAJ | 학술논문

目的：分析非瓣膜性心房颤动（nonvalvular atrial fibrillation， NVAF）患者发生脑卒中的有关危险因素。方法收集168例 NVAF 患者临床资料，比较纳入研究的心房颤动患者中合并脑卒中与未合并脑卒中患者的临床特征，分析非瓣膜性心房颤动患者发生脑卒中的危险因素。结果本研究中房颤合并脑卒中的患病率是27．4％。经统计学分析，高龄（年龄＞75岁）、糖尿病病史、高血压病史、心力衰竭病史等是非瓣膜性心房颤动患者发生脑卒中的危险因素；多因素 Logistic 分析显示：年龄、高血压病史、LVEF ＜50％是发生脑卒中的独立危险因素。结论高龄、高血压病史、左室收缩功能障碍是非瓣膜性心房颤动患者发生脑卒中的独立危险因素。
목적：분석비판막성심방전동（nonvalvular atrial fibrillation， NVAF）환자발생뇌졸중적유관위험인소。방법수집168례 NVAF 환자림상자료，비교납입연구적심방전동환자중합병뇌졸중여미합병뇌졸중환자적림상특정，분석비판막성심방전동환자발생뇌졸중적위험인소。결과본연구중방전합병뇌졸중적환병솔시27．4％。경통계학분석，고령（년령＞75세）、당뇨병병사、고혈압병사、심력쇠갈병사등시비판막성심방전동환자발생뇌졸중적위험인소；다인소 Logistic 분석현시：년령、고혈압병사、LVEF ＜50％시발생뇌졸중적독립위험인소。결론고령、고혈압병사、좌실수축공능장애시비판막성심방전동환자발생뇌졸중적독립위험인소。
Objective To recognize the factors that contribute to the illness of cerebral apoplexy in patients with nonvalvular atrial fibrillation (NVAF).Method The clinical data of 168 NVAF patients were collected and compared with the data of those with no cerebral apoplexy.Case -control study was applied to identify the risk factors that contribute to the illness of cerebral apoplexy in patients with NVAF.Findings The morbidity rate of the subjects of our study was 27.38%.The univariate analysis we conducted indicated that senility( >75 years), diabetes, hypertension and heart failure were the leading factors resulting in cerebral apoplexy in patients with NVAF.And the multivariable logistic regression analysis indicated that senility, hypertension and left ventricular systolic dysfunction (LVEF <50%) were the independent factors that lead to cerebral apoplexy in patients with NVAF.Conclusion senility, hypertension and left ventricular systolic dysfunction were independent risk factors for the illness of cerebral apoplexy in patients with NVAF.