CAJ | 학술논문

目的：介绍基底节区生殖细胞瘤的临床和影像学特点。方法：回顾性分析我科活检病理证实的35例基底节区生殖细胞瘤的临床资料和影像学特点，并行统计学分析常见影像特征与临床特点的关系。结果：男性30例，女性5例，症状为缓慢进行性肢体偏瘫12例。平均年龄(18.3±1.5)岁，病程平均(8±1.6)个月。影像学上5例呈多发病灶，30例单发，出血2例，钙化2例，囊变16例，同侧大脑皮质及大脑脚萎缩16例，不均匀轻度或中度增强，瘤周水肿较轻，占位效应不明显，平均肿瘤最大径3.2±0.2 cm。所有患者均行立体定向活检手术明确病理诊断，无手术并发症。仅肿瘤最大径与是否伴有皮质或脑干萎缩有近似统计学差异(P=0.075)。结论：基底节区生殖细胞瘤临床上以青年男性多见，肢体偏瘫为常见症状，影像学上囊变多见，占位效应及瘤周水肿不明显，如同时伴有同侧大脑皮质及大脑脚萎缩则应高度怀疑，此时应通过穿刺活检明确病理或试验性放疗排除。
목적：개소기저절구생식세포류적림상화영상학특점。방법：회고성분석아과활검병리증실적35례기저절구생식세포류적림상자료화영상학특점，병행통계학분석상견영상특정여림상특점적관계。결과：남성30례，녀성5례，증상위완만진행성지체편탄12례。평균년령(18.3±1.5)세，병정평균(8±1.6)개월。영상학상5례정다발병조，30례단발，출혈2례，개화2례，낭변16례，동측대뇌피질급대뇌각위축16례，불균균경도혹중도증강，류주수종교경，점위효응불명현，평균종류최대경3.2±0.2 cm。소유환자균행입체정향활검수술명학병리진단，무수술병발증。부종류최대경여시부반유피질혹뇌간위축유근사통계학차이(P=0.075)。결론：기저절구생식세포류림상상이청년남성다견，지체편탄위상견증상，영상학상낭변다견，점위효응급류주수종불명현，여동시반유동측대뇌피질급대뇌각위축칙응고도부의，차시응통과천자활검명학병리혹시험성방료배제。
Objective:To investigate the clinical and radiological characteristics of basal ganglia germinoma (BGG). Methods:hTirty ifve patients with pathologically conifrmed BGG were enrolled retrospectively. Results:hTere were 30 males and 5 females, with mean age of 18 years. Hemiparalysis and high intracranial pressure were major symptoms. Imaging showed that cytolization, ipsilateral cerebral or brain stem atrophy, slight mass effect were frequent in BGGs. Chi-square test was used to analyze where ipsilateral cerebral or brain stem atrophy correlated with sex, hemiparalysis, cytolization and tumor size. There were no surgical complications. Only tumoe size showed marginally statistical signiifcance with ipsilateral cerebral or brain stem atrophy (P=0.075). Conclusion:BGG characterized young male, hemiparalysis, cytolization, slight mass effect and ipsilateral cerebral or brain stem atrophy.