中华眼外伤职业眼病杂志
中華眼外傷職業眼病雜誌
중화안외상직업안병잡지
CHINESE JOURNAL OF OCULAR TRAUMA AND OCCUPATIONAL EYE DISEASE
2015年
4期
269-273
,共5页
郝晓璐%侯豹可%李莹%姚毅
郝曉璐%侯豹可%李瑩%姚毅
학효로%후표가%리형%요의
糖尿病视网膜病变%光凝术,激光%氪激光%光学相干断层扫描术
糖尿病視網膜病變%光凝術,激光%氪激光%光學相榦斷層掃描術
당뇨병시망막병변%광응술,격광%극격광%광학상간단층소묘술
Retinopathy,diabetic%Photocoagulation,laser%Krypton laser%Optical coherence tomography
目的 观察不同波长的氪激光广泛视网膜光凝治疗糖尿病视网膜病变其光斑损伤修复的变化情况.方法 前瞻性病例对照研究.选取双眼糖尿病视网膜病变30例(60眼),随机分为氪绿激光组(30右眼)和氪黄激光组(30左眼),分别进行广泛视网膜光凝治疗,并于光凝前、光凝后1h、1周、2周、4周随访,进行光学相干断层扫描(OCT)检查,扫描视盘鼻侧光凝区激光斑的厚度,统计并分析对比两种不同波长的激光对视网膜厚度变化的差异.对同一只眼不同时间点的光斑厚度采用配对样本t检验,对左右眼激光斑的变化情况采用独立样本t检验.结果 30例(60眼)分别用氪黄、氪绿激光光凝后,对比激光前后视网膜厚度的变化.激光前后同一只眼视网膜的平均厚度:激光后视网膜水肿,厚度增加8.4％,1周时变薄减少9.5％,2周时减少17.1％,差异均有统计学意义.4周时与2周时相同.比较左右眼同一时间点视网膜厚度的变化,显示其差异无统计学意义.结论 氪绿激光和氪黄激光均可以有效治疗糖尿病性视网膜病变,二者对视网膜色素上皮层的损伤效果差异无统计学意义,激光光凝后即时视网膜厚度增加10％左右,2周后视网膜厚度变薄且稳定.
目的 觀察不同波長的氪激光廣汎視網膜光凝治療糖尿病視網膜病變其光斑損傷脩複的變化情況.方法 前瞻性病例對照研究.選取雙眼糖尿病視網膜病變30例(60眼),隨機分為氪綠激光組(30右眼)和氪黃激光組(30左眼),分彆進行廣汎視網膜光凝治療,併于光凝前、光凝後1h、1週、2週、4週隨訪,進行光學相榦斷層掃描(OCT)檢查,掃描視盤鼻側光凝區激光斑的厚度,統計併分析對比兩種不同波長的激光對視網膜厚度變化的差異.對同一隻眼不同時間點的光斑厚度採用配對樣本t檢驗,對左右眼激光斑的變化情況採用獨立樣本t檢驗.結果 30例(60眼)分彆用氪黃、氪綠激光光凝後,對比激光前後視網膜厚度的變化.激光前後同一隻眼視網膜的平均厚度:激光後視網膜水腫,厚度增加8.4％,1週時變薄減少9.5％,2週時減少17.1％,差異均有統計學意義.4週時與2週時相同.比較左右眼同一時間點視網膜厚度的變化,顯示其差異無統計學意義.結論 氪綠激光和氪黃激光均可以有效治療糖尿病性視網膜病變,二者對視網膜色素上皮層的損傷效果差異無統計學意義,激光光凝後即時視網膜厚度增加10％左右,2週後視網膜厚度變薄且穩定.
목적 관찰불동파장적극격광엄범시망막광응치료당뇨병시망막병변기광반손상수복적변화정황.방법 전첨성병례대조연구.선취쌍안당뇨병시망막병변30례(60안),수궤분위극록격광조(30우안)화극황격광조(30좌안),분별진행엄범시망막광응치료,병우광응전、광응후1h、1주、2주、4주수방,진행광학상간단층소묘(OCT)검사,소묘시반비측광응구격광반적후도,통계병분석대비량충불동파장적격광대시망막후도변화적차이.대동일지안불동시간점적광반후도채용배대양본t검험,대좌우안격광반적변화정황채용독립양본t검험.결과 30례(60안)분별용극황、극록격광광응후,대비격광전후시망막후도적변화.격광전후동일지안시망막적평균후도:격광후시망막수종,후도증가8.4％,1주시변박감소9.5％,2주시감소17.1％,차이균유통계학의의.4주시여2주시상동.비교좌우안동일시간점시망막후도적변화,현시기차이무통계학의의.결론 극록격광화극황격광균가이유효치료당뇨병성시망막병변,이자대시망막색소상피층적손상효과차이무통계학의의,격광광응후즉시시망막후도증가10％좌우,2주후시망막후도변박차은정.
Objective To observe the damage and recovecry of panretinal photocoagulation (PRP) by different wavelengths of krypton laser on retina in eyes with proliferative diabetic retinopathy.Methods This was a prospective case-control study of 60 eyes (30 right eyes as krypton green laser group and 30 left eyes as krypton yellow laser group) from 30 patients diagnosed as proliferative diabetic retinopathy.They were treated with panretinal photocoagulation (PRP) by a wavelength of 532 nm of krypton green laser and a wavelength of 561 nm of krypton yellow laser respectively.Baseline and morphological changes of optical coherence tomography (OCT) were evaluated before PRP one hour,one week,two weeks,and four weeks after PRP.The thickness of laser spot on nasal optic area was recorded and compared.The thickness of the laser spot of the same eye at different time points were analyzed by using paired sample t-test,while the thickness of the laser spot of the different eyes at the same time point were analyzed by using independent sample t-test.Results Sixty eyes of 30 patients received krypton green laser and krypton yellow laser for PRP respectively.The retinal thickness before PRP was measured as baseline and compared with that at one hour,one week,two weeks,and four weeks after PRP.OCT showed morphological changes of the same eye after PRP:mean retinal thickness was increased by 8.4％ at one hour,and dropped as early as one week by 9.5％ while 17.1％ at two weeks.It remained stable and unchanging at four weeks compared with the data at two weeks.The difference between different time points was statistically significant.No statistically significant difference was found between different eyes at the same time point.Conclusion Krypton green laser and krypton yellow laser all are effective in treating diabetic retinopathy,and there was no statistically significant difference between them in the effect of pigment epithelium layer of retina.The retinal thickness increased by 10％ after PRP and kept stable at two weeks after PRP.
