器官移植
器官移植
기관이식
OGRAN TRANSPLANTATION
2015年
3期
184-189
,共6页
李智斌%张更%刘克普%阮东丽%马帅军%杨晓剑%秦卫军%袁建林
李智斌%張更%劉剋普%阮東麗%馬帥軍%楊曉劍%秦衛軍%袁建林
리지빈%장경%류극보%원동려%마수군%양효검%진위군%원건림
肾移植%慢性腹泻%免疫抑制剂%诊断%治疗%并发症
腎移植%慢性腹瀉%免疫抑製劑%診斷%治療%併髮癥
신이식%만성복사%면역억제제%진단%치료%병발증
Renal transplantation%Chronic diarrhea%Immunosuppressant%Diagnosis%Treatment%Complication
目的：探讨肾移植术后患者慢性腹泻的诊治方案。方法回顾性分析2007年1月至2014年6月在西京医院泌尿外科实施同种异体肾移植术并规律随访的353例患者中发生慢性腹泻者的临床资料。观察肾移植术后慢性腹泻的发生情况（发生率、发生时间、病程、并发症），记录慢性腹泻患者的一般状况与辅助检查指标变化（体重指数、贫血情况、辅助检查指标），以及患者的治疗经过与预后。结果353例肾移植患者中15例（4.2％）发生慢性腹泻，给予积极对症、病因治疗的时间为（15±7）d，腹泻期间死亡2例（分别死于消化道出血和严重低钾血症猝死），其余患者的腹泻均治愈。13例患者随访期间预后良好5例，死亡2例（均死于肺部感染），移植肾失功5例，移植肾功能不全1例。结论肾移植术后慢性腹泻病因复杂，应积极对症、病因治疗，合并严重并发症者预后不良。
目的：探討腎移植術後患者慢性腹瀉的診治方案。方法迴顧性分析2007年1月至2014年6月在西京醫院泌尿外科實施同種異體腎移植術併規律隨訪的353例患者中髮生慢性腹瀉者的臨床資料。觀察腎移植術後慢性腹瀉的髮生情況（髮生率、髮生時間、病程、併髮癥），記錄慢性腹瀉患者的一般狀況與輔助檢查指標變化（體重指數、貧血情況、輔助檢查指標），以及患者的治療經過與預後。結果353例腎移植患者中15例（4.2％）髮生慢性腹瀉，給予積極對癥、病因治療的時間為（15±7）d，腹瀉期間死亡2例（分彆死于消化道齣血和嚴重低鉀血癥猝死），其餘患者的腹瀉均治愈。13例患者隨訪期間預後良好5例，死亡2例（均死于肺部感染），移植腎失功5例，移植腎功能不全1例。結論腎移植術後慢性腹瀉病因複雜，應積極對癥、病因治療，閤併嚴重併髮癥者預後不良。
목적：탐토신이식술후환자만성복사적진치방안。방법회고성분석2007년1월지2014년6월재서경의원비뇨외과실시동충이체신이식술병규률수방적353례환자중발생만성복사자적림상자료。관찰신이식술후만성복사적발생정황（발생솔、발생시간、병정、병발증），기록만성복사환자적일반상황여보조검사지표변화（체중지수、빈혈정황、보조검사지표），이급환자적치료경과여예후。결과353례신이식환자중15례（4.2％）발생만성복사，급여적겁대증、병인치료적시간위（15±7）d，복사기간사망2례（분별사우소화도출혈화엄중저갑혈증졸사），기여환자적복사균치유。13례환자수방기간예후량호5례，사망2례（균사우폐부감염），이식신실공5례，이식신공능불전1례。결론신이식술후만성복사병인복잡，응적겁대증、병인치료，합병엄중병발증자예후불량。
Objective To investigate the diagnosis and treatment regimen for patients with chronic diarrhea after renal transplantation.Methods The clinical data of 353 patients with chronic diarrhea who underwent renal allograft transplantation at Department of Urology of Xijing Hospital from January 2007 to June 2014 with regular follow-up were analyzed retrospectively.The occurrence of chronic diarrhea after renal transplantation was observed,including incidence,time of occurrence,course of disease and complications. The changes in general conditions and auxiliary examination indexes (body mass index,anemia and other auxiliary examination indexes),treatment and prognosis of the patients with chronic diarrhea were recorded. Results Fifteen cases (4.2%) of 353 renal transplant recipients had chronic diarrhea. The time of symptomatic and etiological treatment was (15 ±7 ) d.Two patients died during diarrhea (died from gastrointestinal hemorrhage and sudden death caused by severe hypokalemia respectively)and other patients were recovered.Among the 13 patients,5 cases had good prognosis,2 cases died (both died from pulmonary infection),5 cases suffered from renal allograft dysfunction and 1 case suffered from renal allograft insufficiency during the follow-up.Conclusions The etiology of chronic diarrhea after renal transplantation is complex and the patients should receive symptomatic and etiological treatment.The patients with chronic diarrhea after renal transplantation combined with severe complications have poor prognosis.
