器官移植
器官移植
기관이식
OGRAN TRANSPLANTATION
2015年
3期
194-196,205
,共4页
造血干细胞移植%甲状腺功能亢进%弥漫性毒性甲状腺肿%临床表现%早期诊断
造血榦細胞移植%甲狀腺功能亢進%瀰漫性毒性甲狀腺腫%臨床錶現%早期診斷
조혈간세포이식%갑상선공능항진%미만성독성갑상선종%림상표현%조기진단
Hematopoietic stem cell transplantation%Hyperthyroidism%Diffuse toxic goiter%Clinical manifestation%Early diagnosis
目的：探讨异基因造血干细胞移植术后发生甲状腺功能亢进（甲亢）的诊治特点。方法回顾性分析2008年12月在中山大学附属第三医院血液科行异基因造血干细胞移植术后发生甲亢的1例女性患者的临床资料，总结分析该例患者的临床表现、实验室检查以及诊治经过，并复习相关文献。结果该患者异基因造血干细胞移植术后39个月出现甲亢症状，患者有甲亢特异性临床表现和实验室检查结果，诊断为弥漫性毒性甲状腺肿（Graves 病），给予药物治疗后效果良好。结论异基因造血干细胞移植术后发生甲亢临床少见，有特异性临床表现，确诊主要依靠实验室检查。该病如早期诊断和治疗，疗效良好。
目的：探討異基因造血榦細胞移植術後髮生甲狀腺功能亢進（甲亢）的診治特點。方法迴顧性分析2008年12月在中山大學附屬第三醫院血液科行異基因造血榦細胞移植術後髮生甲亢的1例女性患者的臨床資料，總結分析該例患者的臨床錶現、實驗室檢查以及診治經過，併複習相關文獻。結果該患者異基因造血榦細胞移植術後39箇月齣現甲亢癥狀，患者有甲亢特異性臨床錶現和實驗室檢查結果，診斷為瀰漫性毒性甲狀腺腫（Graves 病），給予藥物治療後效果良好。結論異基因造血榦細胞移植術後髮生甲亢臨床少見，有特異性臨床錶現，確診主要依靠實驗室檢查。該病如早期診斷和治療，療效良好。
목적：탐토이기인조혈간세포이식술후발생갑상선공능항진（갑항）적진치특점。방법회고성분석2008년12월재중산대학부속제삼의원혈액과행이기인조혈간세포이식술후발생갑항적1례녀성환자적림상자료，총결분석해례환자적림상표현、실험실검사이급진치경과，병복습상관문헌。결과해환자이기인조혈간세포이식술후39개월출현갑항증상，환자유갑항특이성림상표현화실험실검사결과，진단위미만성독성갑상선종（Graves 병），급여약물치료후효과량호。결론이기인조혈간세포이식술후발생갑항림상소견，유특이성림상표현，학진주요의고실험실검사。해병여조기진단화치료，료효량호。
Objective To investigate the characteristics of diagnosis and treatment on hyperthyroidism after allogeneic hematopoietic stem cell transplantation (AHSCT).Methods The clinical data of a female patient who suffered from hyperthyroidism after AHSCT at Department of Hematology of the Third Affiliated Hospital,Sun Yat-sen University at December 2008 were analyzed retrospectively.The clinical manifestation,laboratory examination,diagnosis and treatment of the patient were summarized and analyzed, and the relevant literatures were reviewed.Results The patient developed the symptoms of hyperthyroidism at 39 months after AHSCT,and had the clinical manifestation and laboratory examination results specific to hyperthyroidism.The patient was diagnosed as diffuse toxic goiter (Graves’disease)and had good prognosis after drug therapy.Conclusions It is rare to develop hyperthyroidism after AHSCT that has specific clinical manifestation and can be confirmed by laboratory examination.Graves'disease has good prognosis with early diagnosis and treatment.
