CAJ | 학술논문

目的探讨广州地区生殖支原体(Mg)的感染情况及其致病性.方法应用Taqman MGB荧光PCR方法对广东省皮肤性病防治中心2010-2013年性病门诊的2 633例患者宫颈、尿道拭子进行Mg检测,涂片检测念珠菌、阴道毛滴虫和细菌学阴道病,ELISA法检测衣原体,培养法分离淋球菌.结果 2 633例疑似病例经检测Mg阳性209例,总感染率为7.94％,其中男性Mg感染率为8.94％ (175/1 958),女性感染率为5.04％ (34/675),两者比较差异有统计学意义(x2=10.45,P＜0.01).男性感染者主要集中在30～49岁,占77.14％(135/175);女性主要集中在20～39岁,占82.35％(28/34).男性Mg感染者中,30～39岁组占45.14％(79/175),高于其他年龄组,同时也高于女性该年龄组[35.29％ (12/34)],但两者比较差异无统计学意义(x2=1.12,P＞0.05);女性Mg感染者中,20～29岁组占47.06％,高于其他年龄组,同时也高于男性该年龄组[14.29％(25/175)],差异有统计学意义(X2=19.39,P＜0.01).92份男性尿道拭子检出非淋菌性尿道炎(NGU)共33例,其中单纯Mg感染引起的男性NGU占72.73％(24/33).21份宫颈拭子检出宫颈炎17例,其中单纯Mg感染引起的女性宫颈炎占82.35％(14/17).结论广州地区男性Mg感染率明显高于女性,且不同年龄段男女Mg感染情况并不相同,另外Mg感染可能与男性NGU及女性宫颈炎相关.
목적 탐토엄주지구생식지원체(Mg)적감염정황급기치병성.방법 응용Taqman MGB형광PCR방법대광동성피부성병방치중심2010-2013년성병문진적2 633례환자궁경、뇨도식자진행Mg검측,도편검측념주균、음도모적충화세균학음도병,ELISA법검측의원체,배양법분리림구균.결과 2 633례의사병례경검측Mg양성209례,총감염솔위7.94％,기중남성Mg감염솔위8.94％ (175/1 958),녀성감염솔위5.04％ (34/675),량자비교차이유통계학의의(x2=10.45,P＜0.01).남성감염자주요집중재30～49세,점77.14％(135/175);녀성주요집중재20～39세,점82.35％(28/34).남성Mg감염자중,30～39세조점45.14％(79/175),고우기타년령조,동시야고우녀성해년령조[35.29％ (12/34)],단량자비교차이무통계학의의(x2=1.12,P＞0.05);녀성Mg감염자중,20～29세조점47.06％,고우기타년령조,동시야고우남성해년령조[14.29％(25/175)],차이유통계학의의(X2=19.39,P＜0.01).92빈남성뇨도식자검출비림균성뇨도염(NGU)공33례,기중단순Mg감염인기적남성NGU점72.73％(24/33).21빈궁경식자검출궁경염17례,기중단순Mg감염인기적녀성궁경염점82.35％(14/17).결론 엄주지구남성Mg감염솔명현고우녀성,차불동년령단남녀Mg감염정황병불상동,령외Mg감염가능여남성NGU급녀성궁경염상관.
Objective To investigate the infection status and the pathogenicity of Mycoplasma genitalium (Mg) in Guangzhou.Methods A total of 2 633 swab specimen from focus of male and female genital tract were collected from Guangdong Provincial Center for Skin Diseases and STIs Control and Prevention from 2010 to 2013,and Taqman MGB realtime PCR method was applied to detect nucleate of Mg.Trichomonas vaginalis,Candida and bacterial vaginosis were detected by smear,Chlamydia trachomatis by ELISA and Gonococcus by culture.Results The total infection rate of Mg was 7.94％ (209/2 633),positive ratio in male [8.94％ (175/1 958] was significantly higher than positive ratio in female[5.04％ (34/675)] (x2=10.45,P＜0.01).The main age range of Mg infections in males was 30-49 years,the positive ratio of which was up to 77.14％ (135/175).For females,the main age range of Mg infections focused on 20-39 years,the positive ratio of which was arrived 82.35％(28/34).Among the infected males,the age group of 30-39 years took up of 45.14％(791/175) which was higher than other age groups and 35.29％ of infected females aged 30-39 years (12/34).However,the differences had no statistical significance (x2=1.12,P＞0.05).Among the infected females,age group of 20-29 years took up of 47.06％ which was higher than other age groups and 14.29％ of infected males in the same age group (25/175).The differences were statistically significant (x2=19.39,P＜0.01).There were 33 nongonococcal urethritis cases among 92 male urethral swabs,of which 72.73％ (24/33) were Mg-infected.Among 17 cervicitis cases tested from 21 cervical swabs,82.35％ (14/17) were Mg-infected females.Conclusions The Mg infection rate of males is significantly higher than females in Guangzhou.In different age ranges,the Mg infection rates of females and males are also significantly different.In addition,the Mg infection maybe relevant to the non-gonococcal urethritis in men and mucinous cervicitis in women.