世界中西医结合杂志
世界中西醫結閤雜誌
세계중서의결합잡지
WORLD JOURNAL OF TRADITIONAL CHINESE AND WESTERN MEDICINE
2015年
5期
709-712
,共4页
非小细胞肺癌%中医%细胞免疫%埃克替尼
非小細胞肺癌%中醫%細胞免疫%埃剋替尼
비소세포폐암%중의%세포면역%애극체니
Non - Small Cell Lung Cancer%TCM%Cellular Immunity%Icotinib Hydrochloride Tablets
目的：本研究旨在动态观察分析中医治疗促进Ⅳ肺腺癌老年患者长生存的细胞免疫及健康状态的作用效果。方法1个月常规中医治疗为主并定时随访患者体能健康状态及外周血细胞免疫情况、肿瘤标志物值、胸部 CT 等资料，收集相关数据汇总比较分析。结果中医治疗后，体重一直保持稳定（均值是41.3 Kg）；健康状况 KPS 评分逐渐提高（由60分增至80分）；外周血淋巴细胞、总 T 细胞、辅助性 T 细胞、细胞毒 T 细胞、B 细胞，NK 细胞的绝对值呈渐进式波动增高。目前患者生存期21个月较国内外报道中西医治疗组高9个月，较西医组高13个月。结论医能改善健康状况、稳定体重、促进免疫细胞增长及稳定、提高免疫功能，延缓瘤体进展，延长生存期。对老年晚期肿瘤患者，过度治疗不排除有免疫损伤的可能。中医治疗应扶正为主，祛邪为辅，促进免疫功能的恢复及稳定是延长生存期的关键。
目的：本研究旨在動態觀察分析中醫治療促進Ⅳ肺腺癌老年患者長生存的細胞免疫及健康狀態的作用效果。方法1箇月常規中醫治療為主併定時隨訪患者體能健康狀態及外週血細胞免疫情況、腫瘤標誌物值、胸部 CT 等資料，收集相關數據彙總比較分析。結果中醫治療後，體重一直保持穩定（均值是41.3 Kg）；健康狀況 KPS 評分逐漸提高（由60分增至80分）；外週血淋巴細胞、總 T 細胞、輔助性 T 細胞、細胞毒 T 細胞、B 細胞，NK 細胞的絕對值呈漸進式波動增高。目前患者生存期21箇月較國內外報道中西醫治療組高9箇月，較西醫組高13箇月。結論醫能改善健康狀況、穩定體重、促進免疫細胞增長及穩定、提高免疫功能，延緩瘤體進展，延長生存期。對老年晚期腫瘤患者，過度治療不排除有免疫損傷的可能。中醫治療應扶正為主，祛邪為輔，促進免疫功能的恢複及穩定是延長生存期的關鍵。
목적：본연구지재동태관찰분석중의치료촉진Ⅳ폐선암노년환자장생존적세포면역급건강상태적작용효과。방법1개월상규중의치료위주병정시수방환자체능건강상태급외주혈세포면역정황、종류표지물치、흉부 CT 등자료，수집상관수거회총비교분석。결과중의치료후，체중일직보지은정（균치시41.3 Kg）；건강상황 KPS 평분축점제고（유60분증지80분）；외주혈림파세포、총 T 세포、보조성 T 세포、세포독 T 세포、B 세포，NK 세포적절대치정점진식파동증고。목전환자생존기21개월교국내외보도중서의치료조고9개월，교서의조고13개월。결론의능개선건강상황、은정체중、촉진면역세포증장급은정、제고면역공능，연완류체진전，연장생존기。대노년만기종류환자，과도치료불배제유면역손상적가능。중의치료응부정위주，거사위보，촉진면역공능적회복급은정시연장생존기적관건。
Objective To observe and analyze dynamically the effect of TCM on cellular immunity and health condition for promoting the long - term survival of the senile patients with Ⅳ lung adenocarcino-ma. Methods After the conventional TCM treatment for 1 month,the physical health condition,peripheral blood cellular immune situation,tumor marKer value,chest CT and the others were followed - up regularly. The relevant data were collected and analyzed. Results After TCM treatment,the body weight was Kept sta-ble(mean:41. 3 Kg),KPS score for health condition was improved gradually(60 points to 80 points). The ab-solute values of lymphocytes,total T cells,T helper cells,cytotoxic T cells,B cells and NK cells were in-creased progressively. Currently,the patient's survival was 21 months that was longer than that by 9 months in the reports at home and abroad treated with integrated Chinese and western medicine,and longer than that by 13 months in the treatment of western medicine. Conclusion TCM improves the health condition,stabilizes body weight,promotes immune cell growth and stability,improves immune function,delays tumor progression and prolongs the survival. For the aged patients of cancer at late stage,excessive treatment cannot exclude the possibility of immune injury. TCM strengthens the antipathogenic qi and eliminates the pathogenic factors. Promoting the recovery and stability of immune function with TCM is the Key for prolonging the survival.
