CAJ | 학술논문

目的：探讨不同剂量戊酸雌二醇联合宫内节育器对宫腔粘连术后防止再粘连的临床疗效。方法：收治宫腔粘连患者150例予宫腔粘连分离术后上环，并根据给予雌激素剂量不同分为3 mg/d组，6 mg/d组，9 mg/d 组，每组50例。随访术后月经恢复情况，治疗3个月后复查粘连情况。结果：重度宫腔粘连3 mg/d组与6 mg/d组、6 mg/d组与9 mg/d组临床疗效差异均有统计学意义(P＜0.05)。结论：戊酸雌二醇3 mg/d可有效改善轻、中度宫腔粘连患者月经情况，预防宫腔再粘连，又可规避不必要的药物不良反应风险。加大术后雌激素用药剂量治疗重度宫腔粘连患者可取得理想疗效。
목적：탐토불동제량무산자이순연합궁내절육기대궁강점련술후방지재점련적림상료효。방법：수치궁강점련환자150례여궁강점련분리술후상배，병근거급여자격소제량불동분위3 mg/d조，6 mg/d조，9 mg/d 조，매조50례。수방술후월경회복정황，치료3개월후복사점련정황。결과：중도궁강점련3 mg/d조여6 mg/d조、6 mg/d조여9 mg/d조림상료효차이균유통계학의의(P＜0.05)。결론：무산자이순3 mg/d가유효개선경、중도궁강점련환자월경정황，예방궁강재점련，우가규피불필요적약물불량반응풍험。가대술후자격소용약제량치료중도궁강점련환자가취득이상료효。
Objective:To explore the clinical curative effect of different doses of estradiol valerate combined intrauterine device for the prevention of adhesion after the operation for intrauterine adhesion.Methods:150 cases of patients with intrauterine adhesion were treated with intrauterine device after the operation for intrauterine adhesion and were divided into 3 mg/d group,6 mg/d group and 9 mg/d group according to the given doses of estrogen,with 50 cases in each group.The postoperative menstrual recovery was follow-up visited,the adhesion was reviewed after treatment for 3 months.Results:The clinical curative effect of 3 mg/d group and 6 mg/d group,6 mg/d group and 9 mg/d group with severe intrauterine adhesion had statistically significant difference(P<0.05).Conclusion:Estradiol valerate 3 mg/d could improve the menstrual condition of patients with light,moderate intrauterine adhesion effectively and prevent the intrauterine adhesion,which also could avoid the unnecessary risk of drug adverse reactions.The postoperative estrogen dosage in the treatment of patients with severe intrauterine adhesion was increased in order to obtain ideal curative effect.