中国社区医师
中國社區醫師
중국사구의사
Chinese Community Doctors
2015年
16期
6-6,9
,共2页
茶黄素%肾缺血再灌注损伤%肌酐%尿素氮%一氧化氮
茶黃素%腎缺血再灌註損傷%肌酐%尿素氮%一氧化氮
다황소%신결혈재관주손상%기항%뇨소담%일양화담
Theaflavins%Renal ischemia-reperfusion injury%Creatinine%Urea nitrogen%Nitric oxide
目的：探讨茶黄素对大鼠肾缺血再灌注损伤肌酐(SCr)、尿素氮(BUN)和一氧化氮(NO)含量的影响，并初步探讨影响机制。方法：大鼠36只随机分成假手术组、模型组与用药组。检测各组SCr、BUN和NO含量。结果：与假手术组相比，模型组和用药组血清 SCr、BUN 和 NO 含量升高(P＜0.05)。与模型组相比，用药组的 SCr、BUN、NO含量降低(P＜0.05)。结论：茶黄素可改善大鼠肾缺血再灌注损伤导致的肾功能障碍。
目的：探討茶黃素對大鼠腎缺血再灌註損傷肌酐(SCr)、尿素氮(BUN)和一氧化氮(NO)含量的影響，併初步探討影響機製。方法：大鼠36隻隨機分成假手術組、模型組與用藥組。檢測各組SCr、BUN和NO含量。結果：與假手術組相比，模型組和用藥組血清 SCr、BUN 和 NO 含量升高(P＜0.05)。與模型組相比，用藥組的 SCr、BUN、NO含量降低(P＜0.05)。結論：茶黃素可改善大鼠腎缺血再灌註損傷導緻的腎功能障礙。
목적：탐토다황소대대서신결혈재관주손상기항(SCr)、뇨소담(BUN)화일양화담(NO)함량적영향，병초보탐토영향궤제。방법：대서36지수궤분성가수술조、모형조여용약조。검측각조SCr、BUN화NO함량。결과：여가수술조상비，모형조화용약조혈청 SCr、BUN 화 NO 함량승고(P＜0.05)。여모형조상비，용약조적 SCr、BUN、NO함량강저(P＜0.05)。결론：다황소가개선대서신결혈재관주손상도치적신공능장애。
Objective:To explore the effect of theaflavins on the SCr,BUN and NO content of rats with renal ischemia-reperfusion injury and explore the mechanism preliminarily.Methods:36 rats were randomly divided into the sham-operated group,the model group and the drug group.The creatinine(SCr),urea nitrogen and nitric oxide content of each group were detected.Results:Compared with the sham-operated group,the serum SCr,BUN and NO content of the model group and the drug group increased(P<0.05).Compared with the model group,the SCr,BUN,NO content of the drug group reduced(P<0.05).Conclusion:Theaflavins could improve the renal dysfunction of rats with renal ischemia-reperfusion injury.
