世界中西医结合杂志
世界中西醫結閤雜誌
세계중서의결합잡지
WORLD JOURNAL OF TRADITIONAL CHINESE AND WESTERN MEDICINE
2015年
5期
688-690,702
,共4页
疏风解毒胶囊%慢性鼻窦炎%临床疗效
疏風解毒膠囊%慢性鼻竇炎%臨床療效
소풍해독효낭%만성비두염%림상료효
Shufeng Jiedu Capsules%Chronic Rhinosinusitis%Clinical Efficacy
目的：观察疏风解毒胶囊治疗慢性鼻窦炎不伴鼻息肉（chronic rhinosinusitis without na-sal polyps，CRSsNP）的临床疗效。方法将门诊100例 CRSsNP 患者按就诊时间随机分成治疗组与对照组。对照组予克拉霉素口服、丙酸氟替卡松喷鼻、桃金娘油胶囊口服、鼻腔冲洗等治疗，治疗组在对照组治疗基础上加用疏风解毒胶囊口服，4粒/次，3次/ d。疗程3个月。观察两组患者治疗前后主要症状、体征变化，并评定患者临床治疗效果、不良反应发生情况。结果经3个月治疗后，两组治疗均能显著改善患者预后（P ﹤0.05），但治疗组 VAS 临床症状评分、Lund - Kennedy 评分、SNOT -20条评分明显低于对照组（P ﹤0.05），治疗组总有效率明显高于对照组（P ﹤0.05）。两组均未见严重不良反应发生。结论疏风解毒胶囊能够提高 CRSsNP 临床治疗效果，改善患者生活质量。
目的：觀察疏風解毒膠囊治療慢性鼻竇炎不伴鼻息肉（chronic rhinosinusitis without na-sal polyps，CRSsNP）的臨床療效。方法將門診100例 CRSsNP 患者按就診時間隨機分成治療組與對照組。對照組予剋拉黴素口服、丙痠氟替卡鬆噴鼻、桃金孃油膠囊口服、鼻腔遲洗等治療，治療組在對照組治療基礎上加用疏風解毒膠囊口服，4粒/次，3次/ d。療程3箇月。觀察兩組患者治療前後主要癥狀、體徵變化，併評定患者臨床治療效果、不良反應髮生情況。結果經3箇月治療後，兩組治療均能顯著改善患者預後（P ﹤0.05），但治療組 VAS 臨床癥狀評分、Lund - Kennedy 評分、SNOT -20條評分明顯低于對照組（P ﹤0.05），治療組總有效率明顯高于對照組（P ﹤0.05）。兩組均未見嚴重不良反應髮生。結論疏風解毒膠囊能夠提高 CRSsNP 臨床治療效果，改善患者生活質量。
목적：관찰소풍해독효낭치료만성비두염불반비식육（chronic rhinosinusitis without na-sal polyps，CRSsNP）적림상료효。방법장문진100례 CRSsNP 환자안취진시간수궤분성치료조여대조조。대조조여극랍매소구복、병산불체잡송분비、도금낭유효낭구복、비강충세등치료，치료조재대조조치료기출상가용소풍해독효낭구복，4립/차，3차/ d。료정3개월。관찰량조환자치료전후주요증상、체정변화，병평정환자림상치료효과、불량반응발생정황。결과경3개월치료후，량조치료균능현저개선환자예후（P ﹤0.05），단치료조 VAS 림상증상평분、Lund - Kennedy 평분、SNOT -20조평분명현저우대조조（P ﹤0.05），치료조총유효솔명현고우대조조（P ﹤0.05）。량조균미견엄중불량반응발생。결론소풍해독효낭능구제고 CRSsNP 림상치료효과，개선환자생활질량。
Objective To observe the clinical efficacy on chronic rhinosinusitis(CRS)without nasal polyps treated with shufeng jiedu capsules. Methods One hundred outpatients of CRS without nasal polyps were randomized into a treatment group and a control group according to the visit sequence. In the control group,clarithromycin for oral administration,fluticasone propionate nasal spray,myrtol caspules for oral ad-ministration and nasal rinsing were applied. In the treatment group,on the basis of the treatment as the control group,shufeng jiedu capsules for oral administration was supplemented,4 capsules each time,three times a day. The duration of treatment was 3 months. The changes in the main symptoms and physical signs were ob-served before and after treatment in the patients of the two groups. The clinical efficacy and adverse reactions were evaluated. Results After 3 months treatment,the prognosis was significantly improved in the patients of either group(P ﹤ 0. 05). VAS,clinical symptom score,Lund - Kennedy score and SNOT - 20 score in the treatment group were lower obviously than those in the control group(P ﹤ 0. 05). The total effective rate in the treatment group was higher apparently than that in the control group(P ﹤ 0. 05). The severe adverse reac-tion was not found in the two groups. Conclusion Shufeng jiedu capsules improve the clinical therapeutic effect and the quality of life in the patients of CRS without nasal polyps.
