中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2015年
9期
1306-1308
,共3页
妊娠期高血压疾病%婴儿,新生%血脂%胆红素
妊娠期高血壓疾病%嬰兒,新生%血脂%膽紅素
임신기고혈압질병%영인,신생%혈지%담홍소
Pregnancy induced hypertension%Infant,newborn%Blood,Lipid%Bilirubin
目的 观察妊娠期高血压疾病对足月新生儿脂代谢及胆红素代谢的影响.方法 选取足月新生儿200例,其中母亲健康者100例(对照组),母亲患有妊娠期高血压疾病者100例(观察组),记录婴儿出生体质量,测定脐血三酰甘油(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、脂联素(APN)水平,监测经皮胆红素(TCB),记录出生24 h、48 h、72 h TCB值及峰值.结果 观察组体质量为(2 927±492)g,低于对照组的(3 452±348)g,低体质量发生率高于对照组(x2=25..48,P＜0.01);观察组TG、LDL-C水平分别为(0.6±0.24) mmol/L、(1.95±0.25) mmol/L,高于对照组[TG、LDL-C分别为(0.39 ±0.17) mmol/L、(1.95 ±0.25) mmol/L](t=12.35、2.35,均P＜0.05).观察组HDL-C、APN水平分别为(0.64±0.19)mmol/L、(53.1±12.7)mg/L,低于对照组[HDL-C、APN水平分别为(0.85±0.27) mmol/L、(64.3±10.2) mg/L](t=1.79、7.00,均P＜0.05);观察组出生24h、48 h、72 h胆红素值、胆红素峰值分别为(8.64±2.17) mg/L、(11.06±3.12) mg/L、(10.32±2.47) mg/L、(12.04±2.13) mg/L,高于对照组[24 h、48h、72 h胆红素值、胆红素峰值分别为(3.06±0.94) mg/L、(6.98±1.56) mg/L、(7.26±1.89) mg/L、(9.64±1.98)mg/L],差异均有统计学意义(t=23.48、11.65、9.84、8.27,均P＜0.01).结论 妊娠期高血压疾病导致足月新生儿出生体质量较低,并影响新生儿的胆红素代谢及脂代谢.
目的 觀察妊娠期高血壓疾病對足月新生兒脂代謝及膽紅素代謝的影響.方法 選取足月新生兒200例,其中母親健康者100例(對照組),母親患有妊娠期高血壓疾病者100例(觀察組),記錄嬰兒齣生體質量,測定臍血三酰甘油(TG)、總膽固醇(TC)、高密度脂蛋白膽固醇(HDL-C)、低密度脂蛋白膽固醇(LDL-C)、脂聯素(APN)水平,鑑測經皮膽紅素(TCB),記錄齣生24 h、48 h、72 h TCB值及峰值.結果 觀察組體質量為(2 927±492)g,低于對照組的(3 452±348)g,低體質量髮生率高于對照組(x2=25..48,P＜0.01);觀察組TG、LDL-C水平分彆為(0.6±0.24) mmol/L、(1.95±0.25) mmol/L,高于對照組[TG、LDL-C分彆為(0.39 ±0.17) mmol/L、(1.95 ±0.25) mmol/L](t=12.35、2.35,均P＜0.05).觀察組HDL-C、APN水平分彆為(0.64±0.19)mmol/L、(53.1±12.7)mg/L,低于對照組[HDL-C、APN水平分彆為(0.85±0.27) mmol/L、(64.3±10.2) mg/L](t=1.79、7.00,均P＜0.05);觀察組齣生24h、48 h、72 h膽紅素值、膽紅素峰值分彆為(8.64±2.17) mg/L、(11.06±3.12) mg/L、(10.32±2.47) mg/L、(12.04±2.13) mg/L,高于對照組[24 h、48h、72 h膽紅素值、膽紅素峰值分彆為(3.06±0.94) mg/L、(6.98±1.56) mg/L、(7.26±1.89) mg/L、(9.64±1.98)mg/L],差異均有統計學意義(t=23.48、11.65、9.84、8.27,均P＜0.01).結論 妊娠期高血壓疾病導緻足月新生兒齣生體質量較低,併影響新生兒的膽紅素代謝及脂代謝.
목적 관찰임신기고혈압질병대족월신생인지대사급담홍소대사적영향.방법 선취족월신생인200례,기중모친건강자100례(대조조),모친환유임신기고혈압질병자100례(관찰조),기록영인출생체질량,측정제혈삼선감유(TG)、총담고순(TC)、고밀도지단백담고순(HDL-C)、저밀도지단백담고순(LDL-C)、지련소(APN)수평,감측경피담홍소(TCB),기록출생24 h、48 h、72 h TCB치급봉치.결과 관찰조체질량위(2 927±492)g,저우대조조적(3 452±348)g,저체질량발생솔고우대조조(x2=25..48,P＜0.01);관찰조TG、LDL-C수평분별위(0.6±0.24) mmol/L、(1.95±0.25) mmol/L,고우대조조[TG、LDL-C분별위(0.39 ±0.17) mmol/L、(1.95 ±0.25) mmol/L](t=12.35、2.35,균P＜0.05).관찰조HDL-C、APN수평분별위(0.64±0.19)mmol/L、(53.1±12.7)mg/L,저우대조조[HDL-C、APN수평분별위(0.85±0.27) mmol/L、(64.3±10.2) mg/L](t=1.79、7.00,균P＜0.05);관찰조출생24h、48 h、72 h담홍소치、담홍소봉치분별위(8.64±2.17) mg/L、(11.06±3.12) mg/L、(10.32±2.47) mg/L、(12.04±2.13) mg/L,고우대조조[24 h、48h、72 h담홍소치、담홍소봉치분별위(3.06±0.94) mg/L、(6.98±1.56) mg/L、(7.26±1.89) mg/L、(9.64±1.98)mg/L],차이균유통계학의의(t=23.48、11.65、9.84、8.27,균P＜0.01).결론 임신기고혈압질병도치족월신생인출생체질량교저,병영향신생인적담홍소대사급지대사.
Objective To observe the effects of pregnancy induced hypertension on lipid metabolism and bilirubin metabolism in term neonates.Methods 200 term neonates were selected and divided into the two groups,100 cases whose mother were healthy were control group and another 100 cases whose mother had gestational hypertension were observation group.Birth weight,measured in cord blood triglyceride (TG),total cholesterol (TC) levels,high density lipoprotein (HDL-C),low density lipoprotein (LDL-C),adiponectin (APN) level were recorded.Results Birth weight of the observation group had significantly lower birth weight (2 927 ± 492) g,than the weight of the control group (3 452 ± 348) g.The incidence of lower birth weight was higher than in the observation group.TG,LDL-C levels of the observation group were (0.6 ± 0.24) mmol/L,(1.95 ± 0.25) mmol/L,were higher than those of the control group[(0.39 ± 0.17) mmol/L,(1.95 ± 0.25) mmol/L].There was a statistically significant difference between the groups (t =12.35,2.35,P ＜ 0.01 or P ＜ 0.05).HL-C and APN of the observation group were lower than those of the control group (t =1.79,7.00,all P ＜ 0.05).Bilirubin after bomed 24 hours,48 hours,72 hours and bilirubin peak of the observation group were (8.64 ± 2.17) mg/L,(11.06 ± 3.12) mg/L,(10.32 ± 2.47) mg/L,(12.04 ± 2.13) mg/L and were higher than those of the control group [(3.06 ± 0.94) mg/L,(6.98 ± 1.56) mg/L,(7.26±1.89)mg/L,(9.64±1.98)mg/L](t=23.48,11.65,9.84,8.27,allP＜0.01).Conclusion Maternal PIH may affect birth weight,lipid metabolism and bilirubin metabolism.
