中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2015年
15期
112-114
,共3页
围绝经期功能失调性子宫出血%中药止血汤%米非司酮%性激素
圍絕經期功能失調性子宮齣血%中藥止血湯%米非司酮%性激素
위절경기공능실조성자궁출혈%중약지혈탕%미비사동%성격소
Perimenopausal dysfunctional uterine bleeding%Hemostasis decoction of Chinese herbs%Mifepristone%Sex hormone
目的：探讨米非司酮联合止血汤治疗围绝经期功能失调性子宫出血的临床疗效。方法：选取2010年2月-2013年2月本院收治的112例围绝经期功能失调性子宫出血患者作为研究对象，按随机数字表法分为联合组和对照组各56例，对照组患者单用米非司酮治疗，联合组联合应用米非司酮和中药止血汤，比较两组患者的临床疗效、静脉血性激素LH（黄体生成素）、FSH（卵泡刺激素）、E2（雌激素）的水平变化及复发情况。结果：治疗后，两组患者的各项性激素指标（E2、LH、FSH）均较治疗前显著降低（P<0.05），联合组治疗后的E2、LH、FSH水平均显著低于对照组（P<0.05）；联合组的临床治愈率、总有效率分别为78.57%、96.43%，均显著高于对照组的33.93%、75.00%（P<0.05）；两组的不良反应比较差异无统计学意义（P>0.05），但联合组的复发率显著低于对照组（P<0.05）。结论：米非司酮联合止血汤治疗围绝经期功能失调性子宫出血，可有效调节静脉血性激素水平，改善临床症状，疗效确切，值得推广应用。
目的：探討米非司酮聯閤止血湯治療圍絕經期功能失調性子宮齣血的臨床療效。方法：選取2010年2月-2013年2月本院收治的112例圍絕經期功能失調性子宮齣血患者作為研究對象，按隨機數字錶法分為聯閤組和對照組各56例，對照組患者單用米非司酮治療，聯閤組聯閤應用米非司酮和中藥止血湯，比較兩組患者的臨床療效、靜脈血性激素LH（黃體生成素）、FSH（卵泡刺激素）、E2（雌激素）的水平變化及複髮情況。結果：治療後，兩組患者的各項性激素指標（E2、LH、FSH）均較治療前顯著降低（P<0.05），聯閤組治療後的E2、LH、FSH水平均顯著低于對照組（P<0.05）；聯閤組的臨床治愈率、總有效率分彆為78.57%、96.43%，均顯著高于對照組的33.93%、75.00%（P<0.05）；兩組的不良反應比較差異無統計學意義（P>0.05），但聯閤組的複髮率顯著低于對照組（P<0.05）。結論：米非司酮聯閤止血湯治療圍絕經期功能失調性子宮齣血，可有效調節靜脈血性激素水平，改善臨床癥狀，療效確切，值得推廣應用。
목적：탐토미비사동연합지혈탕치료위절경기공능실조성자궁출혈적림상료효。방법：선취2010년2월-2013년2월본원수치적112례위절경기공능실조성자궁출혈환자작위연구대상，안수궤수자표법분위연합조화대조조각56례，대조조환자단용미비사동치료，연합조연합응용미비사동화중약지혈탕，비교량조환자적림상료효、정맥혈성격소LH（황체생성소）、FSH（란포자격소）、E2（자격소）적수평변화급복발정황。결과：치료후，량조환자적각항성격소지표（E2、LH、FSH）균교치료전현저강저（P<0.05），연합조치료후적E2、LH、FSH수평균현저저우대조조（P<0.05）；연합조적림상치유솔、총유효솔분별위78.57%、96.43%，균현저고우대조조적33.93%、75.00%（P<0.05）；량조적불량반응비교차이무통계학의의（P>0.05），단연합조적복발솔현저저우대조조（P<0.05）。결론：미비사동연합지혈탕치료위절경기공능실조성자궁출혈，가유효조절정맥혈성격소수평，개선림상증상，료효학절，치득추엄응용。
Objective:To investigate the clinical effectiveness of mifepristone with hemostasis decoction of Chinese herbs for perimenopausal dysfunctional uterine bleeding.Method:112 patients with perimenopausal dysfunctional uterine bleeding who received treatment in our hospital from February 2010 to February 2013 were chosen as the research object.They were divided into combination group and control group by the method of random number table, 56 patients each group.The patients in control group were cured by giving the medicine of mifepristone while the patients in combination group were given the mifepristone and hemostasis decoction of Chinese herbs at the same time. The patients in the two groups were compared in their clinical effectiveness, the changes in the level of intravenous blood hormone including LH (Luteinizing Hormone), FSH (Follicle-Stimulating Hormone), E2 (Estrogen) and the Recurrence.Result:All the sex hormone indexes of E2, LH, FSH of the patients in the two groups are remarkably lower than those before treatment (P<0.05).After treatment, the level of E2, LH, FSH in combination group were obviously lower than that in the control group (P<0.05).The clinical cure rate and total effective rate of combination group were respectively 78.57% and 96.43% ,which were higher than the control group of 33.93% and 75.00% (P<0.05).There was not too much difference in adverse reactions between the two groups.However, recurrence of the combination group was remarkably lower than that in control group (P<0.05).Conclusion:During the treatment of perimenopausal dysfunctional uterine bleeding, the application of mifepristone and hemostasis decoction of Chinese herbs can effectively better the level of intravenous blood hormone, improve the clinical symptoms and have curative effect.Thus, it is worth population and application.
