CAJ | 학술논문

目的了解乐清市第二人民医院鲍曼不动杆菌感染的临床分布以及其耐药情况,从而为临床的用药提供参考.方法对2010年1月至2012年1月乐清市第二人民医院检出的406株鲍曼不动杆菌进行回顾性分析,观察其临床分布,并计算常用的几种抗菌药物的耐药率.结果鲍曼不动杆菌感染的主要科室为呼吸内科以及重症监护室,检出率分别为27.3％和19.0％,感染部位主要为呼吸系统,鲍曼不动杆菌检出的主要标本为痰液标本,检出率为56.2％,该菌对亚胺培南、美罗培南以及头孢哌酮/舒巴坦的耐药性相对较低,分别为8.6％、10.6％以及17.0％.结论鲍曼不动杆菌是导致医院感染的重要的病原菌且容易出现多重耐药,对患者的生命产生严重威胁,在临床上需要严格根据药敏情况选用合适的抗生素治疗以减少鲍曼不动杆菌的院内传播.
목적 료해악청시제이인민의원포만불동간균감염적림상분포이급기내약정황,종이위림상적용약제공삼고.방법 대2010년1월지2012년1월악청시제이인민의원검출적406주포만불동간균진행회고성분석,관찰기림상분포,병계산상용적궤충항균약물적내약솔.결과 포만불동간균감염적주요과실위호흡내과이급중증감호실,검출솔분별위27.3％화19.0％,감염부위주요위호흡계통,포만불동간균검출적주요표본위담액표본,검출솔위56.2％,해균대아알배남、미라배남이급두포고동/서파탄적내약성상대교저,분별위8.6％、10.6％이급17.0％.결론 포만불동간균시도치의원감염적중요적병원균차용역출현다중내약,대환자적생명산생엄중위협,재림상상수요엄격근거약민정황선용합괄적항생소치료이감소포만불동간균적원내전파.
Objective To investigate the clinical distribution of Acinetobacter Baumann in our hospital and its drug resistance,provide a reference for clinical medical thereby.Methods A retrospectively analysis for 406 Acinetobacter baumannii detected in our hospital from January 2010 to January 2012 was made,the clinical distribution was observed,and the resistance rates of several commonly used antimicrobial agents was calculated.Results Acinetobacter baumannii infections was mainly detected in respiratory medicine and intensive care unit,the detection rate were 27.3％ and 19.0％,the primarily infection site was the respiratory system,Acinetobacter baumannii was detected mainly from sputum specimens and the detection rate was 56.2％,the resistance rate of imipenem,meropenem and cefoperazone sulbactam was relatively low,which were 8.6％,10.6％ and 17.0％.Conclusion Acinetobacter baumannii is an important cause of nosocomial infections and prone to multidrug-resistant pathogens,it is a serious threat to patients,we must make a strict selection of appropriate antibiotic therapy based on susceptibility to reduce nosocomial transmission of Acinetobacter baumannii.