中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2015年
15期
130-132
,共3页
早孕%复发性流产%宫颈HPV感染%相关性
早孕%複髮性流產%宮頸HPV感染%相關性
조잉%복발성유산%궁경HPV감염%상관성
Early pregnancy%Recurrent abortion%HPV infection%Correlation
目的：探讨复发性流产与宫颈HPV感染的相关性。方法：将本站妇科门诊就诊的早期复发性流产（RSA）98例患者作为实验组，同时期妊娠的非RSA女性95例为对照组，采用PCR法对两组患者进行宫颈HPV基因检测，对比两组患者HPV感染的阳性率及各亚型在HPV感染中的比例。结果：实验组中HPV阳性34例（34.7%），对照组HPV阳性12例（12.6%），实验组HPV阳性率显著高于对照组（χ2=16.186， P<0.001）；实验组HPV阳性中各HPV亚型（除HPV 16）占HPV阳性比例与对照组HPV阳性占各亚型比例比较差异均无统计学意义（P>0.05）；HPV阳性与RSA发生呈正相关性（r=0.259，P<0.001）。结论：早期复发性流产与宫颈HPV感染关联密切，HPV可能参与了RSA的发生。
目的：探討複髮性流產與宮頸HPV感染的相關性。方法：將本站婦科門診就診的早期複髮性流產（RSA）98例患者作為實驗組，同時期妊娠的非RSA女性95例為對照組，採用PCR法對兩組患者進行宮頸HPV基因檢測，對比兩組患者HPV感染的暘性率及各亞型在HPV感染中的比例。結果：實驗組中HPV暘性34例（34.7%），對照組HPV暘性12例（12.6%），實驗組HPV暘性率顯著高于對照組（χ2=16.186， P<0.001）；實驗組HPV暘性中各HPV亞型（除HPV 16）佔HPV暘性比例與對照組HPV暘性佔各亞型比例比較差異均無統計學意義（P>0.05）；HPV暘性與RSA髮生呈正相關性（r=0.259，P<0.001）。結論：早期複髮性流產與宮頸HPV感染關聯密切，HPV可能參與瞭RSA的髮生。
목적：탐토복발성유산여궁경HPV감염적상관성。방법：장본참부과문진취진적조기복발성유산（RSA）98례환자작위실험조，동시기임신적비RSA녀성95례위대조조，채용PCR법대량조환자진행궁경HPV기인검측，대비량조환자HPV감염적양성솔급각아형재HPV감염중적비례。결과：실험조중HPV양성34례（34.7%），대조조HPV양성12례（12.6%），실험조HPV양성솔현저고우대조조（χ2=16.186， P<0.001）；실험조HPV양성중각HPV아형（제HPV 16）점HPV양성비례여대조조HPV양성점각아형비례비교차이균무통계학의의（P>0.05）；HPV양성여RSA발생정정상관성（r=0.259，P<0.001）。결론：조기복발성유산여궁경HPV감염관련밀절，HPV가능삼여료RSA적발생。
Objective:To explore the correlation of HPV infection and early pregnancy recurrent spontaneous abortions.Method:98 patients with early pregnancy recurrent spontaneous abortions were selected as the experimental group.95 pregnant women with non- RSA as the control group.All women were from Family planning service station of huiyang district.PCR method was used to dectect HPV genetic type.The HPV-positive rate and the proportion of different various subtypes in HPV-positive were compared.Result:34 cases(34.7%)with HPV-positive were in the experimental group that was significantly higer than 12 cases(12.6%)with HPV-positive in the control group. (χ2=16.186,P<0.001).The different HPV-positive subtypes(except HPV 16) in total HPV-positive in the experimental group was no significant difference compared with that in the control group (P>0.05).There was significant positive correlation between HPV-positive and RSA occur (r=0.259,P<0.001).Conclusion:Early pregnancy recurrent spontaneous abortions is associated with HPV infection closely, HPV may be involved in the occurrence of RSA.
